Cargando…

Preclinical Large Animal Porcine Models for Cardiac Regeneration and Its Clinical Translation: Role of hiPSC-Derived Cardiomyocytes

Myocardial Infarction (MI) occurs due to a blockage in the coronary artery resulting in ischemia and necrosis of cardiomyocytes in the left ventricular heart muscle. The dying cardiac tissue is replaced with fibrous scar tissue, causing a decrease in myocardial contractility and thus affecting the f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sridharan, Divya, Pracha, Nooruddin, Rana, Schaza Javed, Ahmed, Salmman, Dewani, Anam J., Alvi, Syed Baseeruddin, Mergaye, Muhamad, Ahmed, Uzair, Khan, Mahmood
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093073/ https://www.ncbi.nlm.nih.gov/pubmed/37048163 http://dx.doi.org/10.3390/cells12071090

Ejemplares similares

De novo Drug Delivery Modalities for Treating Damaged Hearts: Current Challenges and Emerging Solutions
por: Alvi, Syed Baseeruddin, et al.
Publicado: (2021)

A mathematical model of hiPSC cardiomyocytes electromechanics
por: Forouzandehmehr, Mohamadamin, et al.
Publicado: (2021)

A One-Stop Protocol to Assess Myocardial Fibrosis in Frozen and Paraffin Sections
por: Sridharan, Divya, et al.
Publicado: (2022)

Practical adoption of state-of-the-art hiPSC-cardiomyocyte differentiation techniques
por: Rupert, Cassady E., et al.
Publicado: (2020)

An in silico hiPSC-Derived Cardiomyocyte Model Built With Genetic Algorithm
por: Akwaboah, Akwasi D., et al.
Publicado: (2021)

Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes
por: Ulmer, Bärbel M., et al.
Publicado: (2018)

Microscopy-based cellular contractility assay for adult, neonatal, and hiPSC cardiomyocytes
por: Scalzo, Sérgio, et al.
Publicado: (2022)

Generation of self-assembling cardiac organoids using hiPSC-derived cardiomyocytes
por: Künzel, Karolina, et al.
Publicado: (2022)

Merits of hiPSC-Derived Cardiomyocytes for In Vitro Research and Testing Drug Toxicity
por: Wang, Ping-Hsien, et al.
Publicado: (2022)

An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes
por: McKeithan, Wesley L., et al.
Publicado: (2017)

Comparison of Zebrafish Larvae and hiPSC Cardiomyocytes for Predicting Drug-Induced Cardiotoxicity in Humans
por: Dyballa, Sylvia, et al.
Publicado: (2019)

Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Do not Improve with Carnitine Supplementation
por: Verkerk, Arie O., et al.
Publicado: (2021)

Sarc-Graph: Automated segmentation, tracking, and analysis of sarcomeres in hiPSC-derived cardiomyocytes
por: Zhao, Bill, et al.
Publicado: (2021)

Expression of Extracellular Vesicle PIWI-Interacting RNAs Throughout hiPSC-Cardiomyocyte Differentiation
por: Louro, Ana F., et al.
Publicado: (2022)

Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrates
por: Pioner, Josè Manuel, et al.
Publicado: (2019)

Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
por: Ito, Emiko, et al.
Publicado: (2019)

Modeling Cardiovascular Diseases with hiPSC-Derived Cardiomyocytes in 2D and 3D Cultures
por: Sacchetto, Claudia, et al.
Publicado: (2020)

Electrophysiology of hiPSC-Cardiomyocytes Co-Cultured with HEK Cells Expressing the Inward Rectifier Channel
por: Costa, Ana Da Silva, et al.
Publicado: (2021)

Does Enhanced Structural Maturity of hiPSC-Cardiomyocytes Better for the Detection of Drug-Induced Cardiotoxicity?
por: Van de Sande, Dieter, et al.
Publicado: (2023)

hiPSC-Derived Cells as Models for Drug Discovery
por: Ofir, Rivka
Publicado: (2021)

Characterizing the secretome of licensed hiPSC-derived MSCs
por: Ramos, Yolande F. M., et al.
Publicado: (2022)

Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs
por: Metzler, Eric, et al.
Publicado: (2022)

Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes
por: Josowitz, Rebecca, et al.
Publicado: (2016)

Modeling Cardiomyopathies in a Dish: State-of-the-Art and Novel Perspectives on hiPSC-Derived Cardiomyocytes Maturation
por: Lodola, Francesco, et al.
Publicado: (2021)

Thyroid hormones regulate cardiac repolarization and QT-interval related gene expression in hiPSC cardiomyocytes
por: Ulivieri, Alessandra, et al.
Publicado: (2022)

Reprogramming of HUVECs into Induced Pluripotent Stem Cells (HiPSCs), Generation and Characterization of HiPSC-Derived Neurons and Astrocytes
por: Haile, Yohannes, et al.
Publicado: (2015)

Comparison and Optimization of hiPSC Forebrain Cortical Differentiation Protocols
por: Muratore, Christina R., et al.
Publicado: (2014)

New considerations for hiPSC-based models of neuropsychiatric disorders
por: Hoffman, Gabriel E., et al.
Publicado: (2018)

The Effect of Uncoated SPIONs on hiPSC-Differentiated Endothelial Cells
por: Salingova, Barbara, et al.
Publicado: (2019)

Considerations in hiPSC-derived cartilage for articular cartilage repair
por: Yamashita, Akihiro, et al.
Publicado: (2018)

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases
por: Trudler, Dorit, et al.
Publicado: (2021)

α-synuclein pathogenesis in hiPSC models of Parkinson’s disease
por: Baena-Montes, Jara M., et al.
Publicado: (2021)

Blinded Contractility Analysis in hiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae
por: Mannhardt, Ingra, et al.
Publicado: (2017)

Maturation of three-dimensional, hiPSC-derived cardiomyocyte spheroids utilizing cyclic, uniaxial stretch and electrical stimulation
por: LaBarge, Wesley, et al.
Publicado: (2019)

SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes
por: Toepfer, Christopher N., et al.
Publicado: (2019)

Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium
por: Rupert, Cassady E., et al.
Publicado: (2020)

Quantitative Evaluation of the Sarcomere Network of Human hiPSC-Derived Cardiomyocytes Using Single-Molecule Localization Microscopy
por: Lemcke, Heiko, et al.
Publicado: (2020)

Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring
por: Li, Junjun, et al.
Publicado: (2020)

p53 Promotes Differentiation of Cardiomyocytes from hiPSC through Wnt Signaling-Mediated Mesendodermal Differentiation
por: Liu, Yuanshu, et al.
Publicado: (2021)

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19
por: Sala, Luca, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_85g7p3htbv3ni3fqen2qqc8oiq