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Computational Methods Summarizing Mutational Patterns in Cancer: Promise and Limitations for Clinical Applications

SIMPLE SUMMARY: Cancer is a complex disease that develops over time through accumulated mutations in DNA that transform normal cells into a cancerous state. To fully capture the complexity of the cancer genome, computational methods have been developed to summarize the mutational patterns of cancer,...

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Detalles Bibliográficos
Autores principales: Patterson, Andrew, Elbasir, Abdurrahman, Tian, Bin, Auslander, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093138/
https://www.ncbi.nlm.nih.gov/pubmed/37046619
http://dx.doi.org/10.3390/cancers15071958