Patient Derived Organoids (PDOs), Extracellular Matrix (ECM), Tumor Microenvironment (TME) and Drug Screening: State of the Art and Clinical Implications of Ovarian Cancer Organoids in the Era of Precision Medicine

SIMPLE SUMMARY: Ovarian cancer (OC) has the highest mortality rate of any gynecological malignancy due to the advanced-stage diagnosis, high therapeutic resistance, high recurrence rate, and lack of targeted personalized treatments. This requires the development of preclinical models that can mimic...

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Detalles Bibliográficos
Autores principales: Spagnol, Giulia, Sensi, Francesca, De Tommasi, Orazio, Marchetti, Matteo, Bonaldo, Giulio, Xhindoli, Livia, Noventa, Marco, Agostini, Marco, Tozzi, Roberto, Saccardi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093183/
https://www.ncbi.nlm.nih.gov/pubmed/37046719
http://dx.doi.org/10.3390/cancers15072059

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