Cargando…

NEK Family Review and Correlations with Patient Survival Outcomes in Various Cancer Types

SIMPLE SUMMARY: Kinases are biomolecules that control cellular reactions essential for life. Disruptions in kinase expression and activity lead to the development of diseases such as cancer. A great deal of funding and scientific effort has been poured into kinase research, leading to great advancem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Khoa, Boehling, Julia, Tran, Minh N., Cheng, Thomas, Rivera, Andrew, Collins-Burow, Bridgette M., Lee, Sean B., Drewry, David H., Burow, Matthew E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093199/ https://www.ncbi.nlm.nih.gov/pubmed/37046733 http://dx.doi.org/10.3390/cancers15072067

Ejemplares similares

Evaluation of liver kinase B1 downstream signaling expression in various breast cancers and relapse free survival after systemic chemotherapy treatment
por: Nguyen, Khoa, et al.
Publicado: (2021)

GD2+ cancer stem cells in triple-negative breast cancer: mechanisms of resistance to breast cancer therapies
por: Nguyen, Khoa, et al.
Publicado: (2022)

56371 The Signaling Axis of Tumor Suppressor LKB1 in Triple Negative Breast Cancer
por: Nguyen, Khoa, et al.
Publicado: (2021)

436 Examining the Role of Obesity and Leptin Signaling in Triple Negative Breast Cancer
por: Brock, Courtney, et al.
Publicado: (2022)

235 Analysiss of TNBC Cell Lines Cultured a Novel Translational Breast Cancer Microphysiological System (BC-MPS)
por: Hebert, Katherine L., et al.
Publicado: (2022)

Application of a small molecule inhibitor screen approach to identify CXCR4 downstream signaling pathways that promote a mesenchymal and fulvestrant-resistant phenotype in breast cancer cells
por: Matossian, Margarite D., et al.
Publicado: (2021)

Novel application of the published kinase inhibitor set to identify therapeutic targets and pathways in triple negative breast cancer subtypes
por: Matossian, Margarite D., et al.
Publicado: (2017)

Targeting Mcl-1 by a small molecule NSC260594 for triple-negative breast cancer therapy
por: Dong, Shengli, et al.
Publicado: (2023)

Induction of HOXA9 expression in three-dimensional organotypic culture of the Claudin-low breast cancer cells
por: Li, Miao, et al.
Publicado: (2016)

Insulin-Like Growth Factor-1 Signaling Regulates miRNA Expression in MCF-7 Breast Cancer Cell Line
por: Martin, Elizabeth C., et al.
Publicado: (2012)

Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat
por: Tate, Chandra R, et al.
Publicado: (2012)

A Role for Adipocytes and Adipose Stem Cells in the Breast Tumor Microenvironment and Regenerative Medicine
por: Brock, Courtney K., et al.
Publicado: (2021)

miR-155 induced transcriptome changes in the MCF-7 breast cancer cell line leads to enhanced mitogen activated protein kinase signaling
por: Martin, Elizabeth C., et al.
Publicado: (2014)

microRNA regulation of mammalian target of rapamycin expression and activity controls estrogen receptor function and RAD001 sensitivity
por: Martin, Elizabeth C, et al.
Publicado: (2014)

Argonaute 2 Expression Correlates with a Luminal B Breast Cancer Subtype and Induces Estrogen Receptor Alpha Isoform Variation
por: Conger, Adrienne K., et al.
Publicado: (2016)

Liver Kinase B1 Regulates Remodeling of the Tumor Microenvironment in Triple-Negative Breast Cancer
por: King, Connor T., et al.
Publicado: (2022)

Ceritinib is a novel triple negative breast cancer therapeutic agent
por: Dong, Shengli, et al.
Publicado: (2022)

Proteomic analysis of acquired tamoxifen resistance in MCF-7 cells reveals expression signatures associated with enhanced migration
por: Zhou, Changhua, et al.
Publicado: (2012)

Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer
por: Rhodes, Lyndsay V., et al.
Publicado: (2015)

Patient-Derived Xenografts as an Innovative Surrogate Tumor Model for the Investigation of Health Disparities in Triple Negative Breast Cancer
por: Matossian, Margarite D., et al.
Publicado: (2020)

Panobinostat suppresses the mesenchymal phenotype in a novel claudin-low triple negative patient-derived breast cancer model
por: Matossian, Margarite D., et al.
Publicado: (2018)

Inhibition of p38 mitogen-activated protein kinase alters microRNA expression and reverses epithelial-to-mesenchymal transition
por: ANTOON, JAMES W., et al.
Publicado: (2013)

Quantifying Breast Cancer-Driven Fiber Alignment and Collagen Deposition in Primary Human Breast Tissue
por: Gurrala, Rakesh, et al.
Publicado: (2021)

Potential Prognostic Biomarkers of NIMA (Never in Mitosis, Gene A)-Related Kinase (NEK) Family Members in Breast Cancer
por: Anuraga, Gangga, et al.
Publicado: (2021)

Kinase Inhibitor Profile for Human Nek1, Nek6, and Nek7 and Analysis of the Structural Basis for Inhibitor Specificity
por: Moraes, Eduardo Cruz, et al.
Publicado: (2015)

Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization
por: Haq, Tamanna, et al.
Publicado: (2015)

Local Use of Chlorate of Potassa in Open Carcinoma
por: Burow,
Publicado: (1873)

Nek family of kinases in cell cycle, checkpoint control and cancer
por: Moniz, Larissa, et al.
Publicado: (2011)

Expression of the NEK family in normal and cancer tissue: an immunohistochemical study
por: Melo-Hanchuk, Talita Diniz, et al.
Publicado: (2020)

Mitotic Regulation by NEK Kinase Networks
por: Fry, Andrew M., et al.
Publicado: (2017)

Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer
por: Matossian, Margarite D., et al.
Publicado: (2021)

Die Spurrekonstruktion von pp- und $\overline{p}$p-Reaktionen bei 53 GeV Schwerpunktsenergie in einem Streamerkammerexperiment und physikalische Ergebnisse
por: Burow, L
Publicado: (1982)

Untersuchungen zur Baryonproduktion in Proton-Antiproton-Wechselwirkungen bei Schwerpunktenergien von 200 bis 900 GeV
por: Burow, L
Publicado: (1987)

The NIMA-family kinase, Nek1 affects the stability of centrosomes and ciliogenesis
por: White, Mark C, et al.
Publicado: (2008)

Comparisons of De Novo Transcriptome Assemblers in Diploid and Polyploid Species Using Peanut (Arachis spp.) RNA-Seq Data
por: Chopra, Ratan, et al.
Publicado: (2014)

Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models
por: Sabol, Rachel A., et al.
Publicado: (2019)

An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9
por: Richards, Mark W., et al.
Publicado: (2009)

Funnel: towards comfortable event processing
por: Burow, Burkhard D.
Publicado: (1995)

Mixed language programming
por: Burow, B D
Publicado: (1995)

Results from the ZEUS and H1 experiments at HERA on the total photoproduction cross section and its contributions
por: Burow, B D
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_it26mlmsg3kqcvfjk2fll5se7h