Absence of HDAC3 by Matrix Stiffness Promotes Chromatin Remodeling and Fibroblast Activation in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease characterized by progressive and irreversible lung scarring associated with persistent activation of fibroblasts. Epigenetics could integrate diverse microenvironmental signals, such as stiffness, to direct persistent fibroblast acti...

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Detalles Bibliográficos
Autores principales: Toscano-Marquez, Fernanda, Romero, Yair, Espina-Ordoñez, Marco, Cisneros, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093275/
https://www.ncbi.nlm.nih.gov/pubmed/37048093
http://dx.doi.org/10.3390/cells12071020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093275/
https://www.ncbi.nlm.nih.gov/pubmed/37048093
http://dx.doi.org/10.3390/cells12071020

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