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TrkA Co-Receptors: The Janus Face of TrkA?
SIMPLE SUMMARY: NGF was the first growth factor discovered by Rita Levi Montalcini in 1950. TrkA, its high affinity receptor, is an oncogene that is overexpressed in many cancers. However, targeted therapies against TrkA, in particular kinase inhibitors, have not yet demonstrated efficacy in the con...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093326/ https://www.ncbi.nlm.nih.gov/pubmed/37046604 http://dx.doi.org/10.3390/cancers15071943 |