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TrkA Co-Receptors: The Janus Face of TrkA?

SIMPLE SUMMARY: NGF was the first growth factor discovered by Rita Levi Montalcini in 1950. TrkA, its high affinity receptor, is an oncogene that is overexpressed in many cancers. However, targeted therapies against TrkA, in particular kinase inhibitors, have not yet demonstrated efficacy in the con...

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Detalles Bibliográficos
Autores principales: Trouvilliez, Sarah, Lagadec, Chann, Toillon, Robert-Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093326/
https://www.ncbi.nlm.nih.gov/pubmed/37046604
http://dx.doi.org/10.3390/cancers15071943

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