DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies

DPP8/9 inhibition induces either pyroptotic or apoptotic cell death in hematological malignancies. We previously reported that treatment with the DPP8/9 inhibitor 1G244 resulted in apoptotic cell death in myeloma, and our current study further evaluates the mechanism of action of 1G244 in different...

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Detalles Bibliográficos
Autores principales: Kikuchi, Shohei, Wada, Akinori, Kamihara, Yusuke, Okazaki, Kosuke, Jawaid, Paras, Rehman, Mati Ur, Kobayashi, Eiji, Susukida, Takeshi, Minemura, Tomoki, Nabe, Yoshimi, Iwao, Noriaki, Ozawa, Tatsuhiko, Hatano, Ryo, Yamada, Mitsugu, Kishi, Hiroyuki, Matsuya, Yuji, Mizuguchi, Mineyuki, Hayakawa, Yoshihiro, Dang, Nam H., Sakamoto, Yasumitsu, Morimoto, Chikao, Sato, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093441/
https://www.ncbi.nlm.nih.gov/pubmed/37048172
http://dx.doi.org/10.3390/cells12071100

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