Cargando…
Cbfβ Is a Novel Modulator against Osteoarthritis by Maintaining Articular Cartilage Homeostasis through TGF-β Signaling
TGF-β signaling is a vital regulator for maintaining articular cartilage homeostasis. Runx transcription factors, downstream targets of TGF-β signaling, have been studied in the context of osteoarthritis (OA). Although Runx partner core binding factor β (Cbfβ) is known to play a pivotal role in chon...
Autores principales: | Che, Xiangguo, Jin, Xian, Park, Na Rae, Kim, Hee-June, Kyung, Hee-Soo, Kim, Hyun-Ju, Lian, Jane B., Stein, Janet L., Stein, Gary S., Choi, Je-Yong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093452/ https://www.ncbi.nlm.nih.gov/pubmed/37048137 http://dx.doi.org/10.3390/cells12071064 |
Ejemplares similares
-
Runx1 is a key regulator of articular cartilage homeostasis by orchestrating YAP, TGFβ, and Wnt signaling in articular cartilage formation and osteoarthritis
por: Zhang, Yan, et al.
Publicado: (2022) -
TGF-β/Smad3 Signals Repress Chondrocyte Hypertrophic Differentiation and Are Required for Maintaining Articular Cartilage
por: Yang, Xiao, et al.
Publicado: (2001) -
Mechanical stress determines the configuration of TGFβ activation in articular cartilage
por: Zhen, Gehua, et al.
Publicado: (2021) -
TGFβ/BMP Signaling Pathway in Cartilage Homeostasis
por: Thielen, Nathalie G.M., et al.
Publicado: (2019) -
Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis
por: Bian, Qin, et al.
Publicado: (2017)