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“Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax
A pneumothorax is a condition that occurs in the lung region when air enters the pleural space—the area between the lung and chest wall—causing the lung to collapse and making it difficult to breathe. This can happen spontaneously or as a result of an injury. The symptoms of a pneumothorax may inclu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093601/ https://www.ncbi.nlm.nih.gov/pubmed/37046523 http://dx.doi.org/10.3390/diagnostics13071305 |
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author | Kumar, V. Dhilip Rajesh, P. Geman, Oana Craciun, Maria Daniela Arif, Muhammad Filip, Roxana |
author_facet | Kumar, V. Dhilip Rajesh, P. Geman, Oana Craciun, Maria Daniela Arif, Muhammad Filip, Roxana |
author_sort | Kumar, V. Dhilip |
collection | PubMed |
description | A pneumothorax is a condition that occurs in the lung region when air enters the pleural space—the area between the lung and chest wall—causing the lung to collapse and making it difficult to breathe. This can happen spontaneously or as a result of an injury. The symptoms of a pneumothorax may include chest pain, shortness of breath, and rapid breathing. Although chest X-rays are commonly used to detect a pneumothorax, locating the affected area visually in X-ray images can be time-consuming and prone to errors. Existing computer technology for detecting this disease from X-rays is limited by three major issues, including class disparity, which causes overfitting, difficulty in detecting dark portions of the images, and vanishing gradient. To address these issues, we propose an ensemble deep learning model called PneumoNet, which uses synthetic images from data augmentation to address the class disparity issue and a segmentation system to identify dark areas. Finally, the issue of the vanishing gradient, which becomes very small during back propagation, can be addressed by hyperparameter optimization techniques that prevent the model from slowly converging and poorly performing. Our model achieved an accuracy of 98.41% on the Society for Imaging Informatics in Medicine pneumothorax dataset, outperforming other deep learning models and reducing the computation complexities in detecting the disease. |
format | Online Article Text |
id | pubmed-10093601 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100936012023-04-13 “Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax Kumar, V. Dhilip Rajesh, P. Geman, Oana Craciun, Maria Daniela Arif, Muhammad Filip, Roxana Diagnostics (Basel) Article A pneumothorax is a condition that occurs in the lung region when air enters the pleural space—the area between the lung and chest wall—causing the lung to collapse and making it difficult to breathe. This can happen spontaneously or as a result of an injury. The symptoms of a pneumothorax may include chest pain, shortness of breath, and rapid breathing. Although chest X-rays are commonly used to detect a pneumothorax, locating the affected area visually in X-ray images can be time-consuming and prone to errors. Existing computer technology for detecting this disease from X-rays is limited by three major issues, including class disparity, which causes overfitting, difficulty in detecting dark portions of the images, and vanishing gradient. To address these issues, we propose an ensemble deep learning model called PneumoNet, which uses synthetic images from data augmentation to address the class disparity issue and a segmentation system to identify dark areas. Finally, the issue of the vanishing gradient, which becomes very small during back propagation, can be addressed by hyperparameter optimization techniques that prevent the model from slowly converging and poorly performing. Our model achieved an accuracy of 98.41% on the Society for Imaging Informatics in Medicine pneumothorax dataset, outperforming other deep learning models and reducing the computation complexities in detecting the disease. MDPI 2023-03-30 /pmc/articles/PMC10093601/ /pubmed/37046523 http://dx.doi.org/10.3390/diagnostics13071305 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kumar, V. Dhilip Rajesh, P. Geman, Oana Craciun, Maria Daniela Arif, Muhammad Filip, Roxana “Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax |
title | “Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax |
title_full | “Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax |
title_fullStr | “Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax |
title_full_unstemmed | “Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax |
title_short | “Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax |
title_sort | “quo vadis diagnosis”: application of informatics in early detection of pneumothorax |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093601/ https://www.ncbi.nlm.nih.gov/pubmed/37046523 http://dx.doi.org/10.3390/diagnostics13071305 |
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