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Genomic landscape and survival analysis of ctDNA “neo-RAS wild-type” patients with originally RAS mutant metastatic colorectal cancer

BACKGROUND: The term “neo-RAS wild-type” refers to the switch to RAS wild-type disease in plasma circulating tumor DNA (ctDNA) from originally RAS mutant colorectal cancers. Consistently, the hypothesis to re-determine RAS mutational status in ctDNA at disease progression in RAS mutant mCRC opened t...

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Detalles Bibliográficos
Autores principales: Nicolazzo, Chiara, Magri, Valentina, Marino, Luca, Belardinilli, Francesca, Di Nicolantonio, Federica, De Renzi, Gianluigi, Caponnetto, Salvatore, De Meo, Michela, Giannini, Giuseppe, Santini, Daniele, Cortesi, Enrico, Gazzaniga, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093715/
https://www.ncbi.nlm.nih.gov/pubmed/37064137
http://dx.doi.org/10.3389/fonc.2023.1160673