Over-Expression of LEDGF/p75 in HEp-2 Cells Enhances Autoimmune IgG Response in Patients with Benign Prostatic Hyperplasia—A Novel Diagnostic Approach with Therapeutic Consequence?

Lens epithelium-derived growth factor splice variant of 75 kDa (LEDGF/p75) is an autoantigen over-expressed in solid tumors and acts as a stress-related transcriptional co-activator. Participation of autoimmune responses in the pathophysiology of benign prostatic hyperplasia (PBH) and a correspondin...

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Detalles Bibliográficos
Autores principales: Liedtke, Victoria, Rose, Laura, Hiemann, Rico, Nasser, Abdullah, Rödiger, Stefan, Bonaventura, Alena, Winkler, Laura, Sowa, Mandy, Stöckle, Michael, Schierack, Peter, Junker, Kerstin, Roggenbuck, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093878/
https://www.ncbi.nlm.nih.gov/pubmed/37047137
http://dx.doi.org/10.3390/ijms24076166

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