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Epi-Impute: Single-Cell RNA-seq Imputation via Integration with Single-Cell ATAC-seq

Single-cell RNA-seq data contains a lot of dropouts hampering downstream analyses due to the low number and inefficient capture of mRNAs in individual cells. Here, we present Epi-Impute, a computational method for dropout imputation by reconciling expression and epigenomic data. Epi-Impute leverages...

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Detalles Bibliográficos
Autores principales:	Raevskiy, Mikhail, Yanvarev, Vladislav, Jung, Sascha, Del Sol, Antonio, Medvedeva, Yulia A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094055/ https://www.ncbi.nlm.nih.gov/pubmed/37047200 http://dx.doi.org/10.3390/ijms24076229

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