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Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections

Ganoderma lucidum is a medicinal mushroom that has been traditionally used in Chinese medicine for centuries. It has been found to have a wide range of medicinal properties, including antioxidant, anti-inflammatory, and immune-boosting effects. Recent research has focused on the potential benefits o...

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Autores principales: Ekiz, Elif, Oz, Emel, Abd El-Aty, A. M., Proestos, Charalampos, Brennan, Charles, Zeng, Maomao, Tomasevic, Igor, Elobeid, Tahra, Çadırcı, Kenan, Bayrak, Muharrem, Oz, Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094145/
https://www.ncbi.nlm.nih.gov/pubmed/37048331
http://dx.doi.org/10.3390/foods12071512
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author Ekiz, Elif
Oz, Emel
Abd El-Aty, A. M.
Proestos, Charalampos
Brennan, Charles
Zeng, Maomao
Tomasevic, Igor
Elobeid, Tahra
Çadırcı, Kenan
Bayrak, Muharrem
Oz, Fatih
author_facet Ekiz, Elif
Oz, Emel
Abd El-Aty, A. M.
Proestos, Charalampos
Brennan, Charles
Zeng, Maomao
Tomasevic, Igor
Elobeid, Tahra
Çadırcı, Kenan
Bayrak, Muharrem
Oz, Fatih
author_sort Ekiz, Elif
collection PubMed
description Ganoderma lucidum is a medicinal mushroom that has been traditionally used in Chinese medicine for centuries. It has been found to have a wide range of medicinal properties, including antioxidant, anti-inflammatory, and immune-boosting effects. Recent research has focused on the potential benefits of G. lucidum in treating metabolic disorders such as diabetes and obesity, as well as its possible role in preventing and treating infections caused by the coronavirus. Triterpenoids are a major group of bioactive compounds found in G. lucidum, and they have a range of biological activities, including anti-inflammatory and antioxidant properties. These compounds have been found to improve insulin sensitivity and lower blood sugar levels in animal models of diabetes. Additionally, G. lucidum polysaccharides have been found to reduce bodyweight and improve glucose metabolism in animal models of obesity. These polysaccharides can also help to increase the activity of certain white blood cells, which play a critical role in the body’s immune response. For coronavirus, some in vitro studies have shown that G. lucidum polysaccharides and triterpenoids have the potential to inhibit coronavirus infection; however, these results have not been validated through clinical trials. Therefore, it would be premature to draw any definitive conclusions about the effectiveness of G. lucidum in preventing or treating coronavirus infections in humans.
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spelling pubmed-100941452023-04-13 Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections Ekiz, Elif Oz, Emel Abd El-Aty, A. M. Proestos, Charalampos Brennan, Charles Zeng, Maomao Tomasevic, Igor Elobeid, Tahra Çadırcı, Kenan Bayrak, Muharrem Oz, Fatih Foods Review Ganoderma lucidum is a medicinal mushroom that has been traditionally used in Chinese medicine for centuries. It has been found to have a wide range of medicinal properties, including antioxidant, anti-inflammatory, and immune-boosting effects. Recent research has focused on the potential benefits of G. lucidum in treating metabolic disorders such as diabetes and obesity, as well as its possible role in preventing and treating infections caused by the coronavirus. Triterpenoids are a major group of bioactive compounds found in G. lucidum, and they have a range of biological activities, including anti-inflammatory and antioxidant properties. These compounds have been found to improve insulin sensitivity and lower blood sugar levels in animal models of diabetes. Additionally, G. lucidum polysaccharides have been found to reduce bodyweight and improve glucose metabolism in animal models of obesity. These polysaccharides can also help to increase the activity of certain white blood cells, which play a critical role in the body’s immune response. For coronavirus, some in vitro studies have shown that G. lucidum polysaccharides and triterpenoids have the potential to inhibit coronavirus infection; however, these results have not been validated through clinical trials. Therefore, it would be premature to draw any definitive conclusions about the effectiveness of G. lucidum in preventing or treating coronavirus infections in humans. MDPI 2023-04-03 /pmc/articles/PMC10094145/ /pubmed/37048331 http://dx.doi.org/10.3390/foods12071512 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ekiz, Elif
Oz, Emel
Abd El-Aty, A. M.
Proestos, Charalampos
Brennan, Charles
Zeng, Maomao
Tomasevic, Igor
Elobeid, Tahra
Çadırcı, Kenan
Bayrak, Muharrem
Oz, Fatih
Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections
title Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections
title_full Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections
title_fullStr Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections
title_full_unstemmed Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections
title_short Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections
title_sort exploring the potential medicinal benefits of ganoderma lucidum: from metabolic disorders to coronavirus infections
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094145/
https://www.ncbi.nlm.nih.gov/pubmed/37048331
http://dx.doi.org/10.3390/foods12071512
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