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Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody

Maternal alloantibodies toward paternally inherited Ags on fetal platelets can cause thrombocytopenia and bleeding complications in the fetus or neonate, referred to as fetal and neonatal alloimmune thrombocytopenia (FNAIT). This is most commonly caused by Abs against the human platelet Ag (HPA)-1a...

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Detalles Bibliográficos
Autores principales: Mørtberg, Trude V., Zhi, Huiying, Vidarsson, Gestur, Foss, Stian, Lissenberg-Thunnissen, Suzanne, Wuhrer, Manfred, Michaelsen, Terje E., Skogen, Bjørn, Stuge, Tor B., Andersen, Jan Terje, Newman, Peter J., Ahlen, Maria Therese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094187/
https://www.ncbi.nlm.nih.gov/pubmed/35074850
http://dx.doi.org/10.4049/immunohorizons.2100097