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Identification of Potential Lead Compounds Targeting Novel Druggable Cavity of SARS-CoV-2 Spike Trimer by Molecular Dynamics Simulations

The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become an urgent public health problem. Spike (S) protein mediates the fusion between the virus and the host cell membranes, consequently emerging as an important target of drug design. The lack of comparisons of...

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Detalles Bibliográficos
Autores principales:	Zhao, Yizhen, Zhao, Yifan, Xie, Linke, Li, Qian, Zhang, Yuze, Zang, Yongjian, Li, Xuhua, Zhang, Lei, Yang, Zhiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094189/ https://www.ncbi.nlm.nih.gov/pubmed/37047254 http://dx.doi.org/10.3390/ijms24076281

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