Cargando…

Hyperglycemia Aggravates Periodontitis via Autophagy Impairment and ROS-Inflammasome-Mediated Macrophage Pyroptosis

Macrophage pyroptosis drives the secretion of IL-1β, which has been recently reported to be a featured salivary biomarker for discriminating periodontitis in the presence of diabetes. This study aimed to explore whether macrophage pyroptosis plays a role in the development of diabetes mellitus–perio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Zhenxing, Ming, Ye, Li, Xiang, Tan, Hao, He, Xinyi, Yang, Lan, Song, Jinlin, Zheng, Leilei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094233/ https://www.ncbi.nlm.nih.gov/pubmed/37047282 http://dx.doi.org/10.3390/ijms24076309

Ejemplares similares

Aquaporin5 Deficiency Aggravates ROS/NLRP3 Inflammasome-Mediated Pyroptosis in the Lacrimal Glands
por: Cao, Xin, et al.
Publicado: (2023)

Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection
por: Byrne, Brenda G., et al.
Publicado: (2013)

Hyperglycemia aggravates acute liver injury by promoting liver‐resident macrophage NLRP3 inflammasome activation via the inhibition of AMPK/mTOR‐mediated autophagy induction
por: Wang, Qi, et al.
Publicado: (2019)

Cathepsin B aggravates coxsackievirus B3-induced myocarditis through activating the inflammasome and promoting pyroptosis
por: Wang, Yaping, et al.
Publicado: (2018)

Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation
por: Wang, Yufang, et al.
Publicado: (2019)

Microcystin-LR Induces and Aggravates Colitis through NLRP3 Inflammasome-Mediated Pyroptosis in Mice
por: Yang, Yue, et al.
Publicado: (2023)

NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
por: Qiu, Zhen, et al.
Publicado: (2017)

Fine particulate matter exposure aggravates ischemic injury via NLRP3 inflammasome activation and pyroptosis
por: Gao, Li, et al.
Publicado: (2022)

Pyroptosis, inflammasome, and gasdermins in tumor immunity
por: Ouyang, Xiaohu, et al.
Publicado: (2023)

Lysosomal storage and impaired autophagy lead to inflammasome activation in Gaucher macrophages
por: Aflaki, Elma, et al.
Publicado: (2015)

Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages
por: Eisfeld, Hannah S., et al.
Publicado: (2021)

Spontaneous NETosis in diabetes: A role of hyperglycemia mediated ROS and autophagy
por: Farhan, Anam, et al.
Publicado: (2023)

Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes
por: Qiu, Zhen, et al.
Publicado: (2019)

S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression
por: Liu, Yan, et al.
Publicado: (2022)

Gardnerella vaginalis induces NLRP3 inflammasome-mediated pyroptosis in macrophages and THP-1 monocytes
por: Xiang, Nan, et al.
Publicado: (2021)

Exacerbated post‐infarct pathological myocardial remodelling in diabetes is associated with impaired autophagy and aggravated NLRP3 inflammasome activation
por: Mao, Shuai, et al.
Publicado: (2021)

Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy
por: Ning, Bangzuo, et al.
Publicado: (2023)

Dec2 inhibits macrophage pyroptosis to promote periodontal homeostasis
por: He, Dawei, et al.
Publicado: (2021)

Pyroptosis and inflammasomes in cancer and inflammation
por: Wang, Jie‐Lin, et al.
Publicado: (2023)

PSMB5 Alleviates Ulcerative Colitis by Inhibiting ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis
por: Han, Liang, et al.
Publicado: (2022)

Pyroptosis in NLRP3 inflammasome-related atherosclerosis
por: Zeng, Xiang, et al.
Publicado: (2022)

MgIG exerts therapeutic effects on crizotinib‐induced hepatotoxicity by limiting ROS‐mediated autophagy and pyroptosis
por: Li, Min, et al.
Publicado: (2022)

Retracted: PSMB5 Alleviates Ulcerative Colitis by Inhibiting ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis
por: Markers, Disease
Publicado: (2023)

HHcy Induces Pyroptosis and Atherosclerosis via the Lipid Raft-Mediated NOX-ROS-NLRP3 Inflammasome Pathway in apoE(−/−) Mice
por: Liu, Sijun, et al.
Publicado: (2022)

HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis
por: Shang, Jiawei, et al.
Publicado: (2023)

Emerging Role of the Inflammasome and Pyroptosis in Hypertension
por: De Miguel, Carmen, et al.
Publicado: (2021)

Bibliometric Analysis of the Inflammasome and Pyroptosis in Brain
por: Chen, Yuhua, et al.
Publicado: (2021)

Pyroptosis and inflammasomes in diabetic wound healing
por: Mu, Xingrui, et al.
Publicado: (2022)

Inflammasome and pyroptosis in autoimmune liver diseases
por: Wang, Jixuan, et al.
Publicado: (2023)

ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages
por: Zha, Qing-Bing, et al.
Publicado: (2016)

Cationic Carbon Nanoparticles Induce Inflammasome-Dependent Pyroptosis in Macrophages via Lysosomal Dysfunction
por: Arezki, Yasmin, et al.
Publicado: (2022)

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis
por: Wang, Lulu, et al.
Publicado: (2021)

Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis
por: Liu, Jian, et al.
Publicado: (2016)

The role of ROS-induced pyroptosis in CVD
por: Tian, Kaijiang, et al.
Publicado: (2023)

Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation
por: Cheng, Yu-Chi, et al.
Publicado: (2020)

Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation
por: Luo, Tianyu, et al.
Publicado: (2022)

Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis
por: Chen, Qin, et al.
Publicado: (2021)

Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion
por: Wang, Wenwen, et al.
Publicado: (2021)

Hyperglycemia aggravates ischemic brain damage via ERK1/2 activated cell autophagy and mitochondrial fission
por: Liu, Ping, et al.
Publicado: (2022)

NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages
por: Liu, Yan-gang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_u6i68klvurqufieuf2e6tgedci