Cargando…

Beyond the TPP(+) “gold standard”: a new generation mitochondrial delivery vector based on extended PN frameworks

Mitochondrial targeting represents an attractive strategy for treating metabolic, degenerative and hyperproliferative diseases, since this organelle plays key roles in essential cellular functions. Triphenylphosphonium (TPP(+)) moieties – the current “gold standard” – have been widely used as mitoch...

Descripción completa

Detalles Bibliográficos
Autores principales: Ong, How Chee, Coimbra, João T. S., Ramos, Maria J., Xing, Bengang, Fernandes, Pedro A., García, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094279/
https://www.ncbi.nlm.nih.gov/pubmed/37063789
http://dx.doi.org/10.1039/d2sc06508h