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Beyond the TPP(+) “gold standard”: a new generation mitochondrial delivery vector based on extended PN frameworks
Mitochondrial targeting represents an attractive strategy for treating metabolic, degenerative and hyperproliferative diseases, since this organelle plays key roles in essential cellular functions. Triphenylphosphonium (TPP(+)) moieties – the current “gold standard” – have been widely used as mitoch...
Autores principales: | Ong, How Chee, Coimbra, João T. S., Ramos, Maria J., Xing, Bengang, Fernandes, Pedro A., García, Felipe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094279/ https://www.ncbi.nlm.nih.gov/pubmed/37063789 http://dx.doi.org/10.1039/d2sc06508h |
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