Cargando…

Anthracycline Therapy Modifies Immune Checkpoint Signaling in the Heart

Cancer survival rates have increased significantly because of improvements in therapy regimes and novel immunomodulatory drugs. Recently, combination therapies of anthracyclines and immune checkpoint inhibitors (ICIs) have been proposed to maximize neoplastic cell removal. However, it has been specu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Korste, Sebastian, Settelmeier, Stephan, Michel, Lars, Odersky, Andrea, Stock, Pia, Reyes, Fabrice, Haj-Yehia, Elias, Anker, Markus S., Grüneboom, Anika, Hendgen-Cotta, Ulrike B., Rassaf, Tienush, Totzeck, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094326/ https://www.ncbi.nlm.nih.gov/pubmed/37047026 http://dx.doi.org/10.3390/ijms24076052

Ejemplares similares

PD1 Deficiency Modifies Cardiac Immunity during Baseline Conditions and in Reperfused Acute Myocardial Infarction
por: Michel, Lars, et al.
Publicado: (2022)

CD47 blockade enhances phagocytosis of cardiac cell debris by neutrophils
por: Haj-Yehia, Elias, et al.
Publicado: (2023)

Crosstalk between Nitrite, Myoglobin and Reactive Oxygen Species to Regulate Vasodilation under Hypoxia
por: Totzeck, Matthias, et al.
Publicado: (2014)

A practical approach to remote ischemic preconditioning and ischemic preconditioning against myocardial ischemia/reperfusion injury
por: Totzeck, Matthias, et al.
Publicado: (2016)

Superiority of focused ion beam‐scanning electron microscope tomography of cardiomyocytes over standard 2D analyses highlighted by unmasking mitochondrial heterogeneity
por: Heinen‐Weiler, Jacqueline, et al.
Publicado: (2021)

Demonstration of the Early Cardiac Bioavailability of a Non-Specific Cell-Targeted Peptide Using Radionuclide-Based Imaging In Vivo
por: Settelmeier, Stephan, et al.
Publicado: (2023)

Right ventricular and atrial strain in patients with advanced melanoma undergoing immune checkpoint inhibitor therapy
por: Pohl, Julia, et al.
Publicado: (2022)

Ventricular assist device for a coronavirus disease 2019‐affected heart
por: Rassaf, Tienush, et al.
Publicado: (2020)

Cardiotoxicity from immune checkpoint inhibitors
por: Michel, Lars, et al.
Publicado: (2019)

Dietary Nitrate Is a Modifier of Vascular Gene Expression in Old Male Mice
por: Rammos, Christos, et al.
Publicado: (2015)

Publisher Correction: Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
por: Merz, Simon F., et al.
Publicado: (2019)

Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
por: Merz, Simon F., et al.
Publicado: (2019)

Myocardial Expression of Macrophage Migration Inhibitory Factor in Patients with Heart Failure
por: Pohl, Julia, et al.
Publicado: (2017)

Modulation of Circulating Macrophage Migration Inhibitory Factor in the Elderly
por: Rammos, Christos, et al.
Publicado: (2014)

Renal replacement therapy neutralizes elevated MIF levels in septic shock
por: Pohl, Julia, et al.
Publicado: (2016)

A novel physiological role for cardiac myoglobin in lipid metabolism
por: Hendgen-Cotta, Ulrike B., et al.
Publicado: (2017)

Cardiac biomarkers for the detection of cardiotoxicity in childhood cancer—a meta‐analysis
por: Michel, Lars, et al.
Publicado: (2020)

Filtration of Macrophage Migration Inhibitory Factor (MIF) in Patients with End Stage Renal Disease Undergoing Hemodialysis
por: Luedike, Peter, et al.
Publicado: (2015)

Percutaneous Mitral Valve Repair in Mitral Regurgitation Reduces Cell-Free Hemoglobin and Improves Endothelial Function
por: Rammos, Christos, et al.
Publicado: (2016)

Cytosolic BNIP3 Dimer Interacts with Mitochondrial BAX Forming Heterodimers in the Mitochondrial Outer Membrane under Basal Conditions
por: Hendgen-Cotta, Ulrike B., et al.
Publicado: (2017)

Capacity changes in German certified chest pain units during COVID-19 outbreak response
por: Settelmeier, Stephan, et al.
Publicado: (2020)

Left Ventricular Diastolic Function Following Anthracycline-Based Chemotherapy in Patients with Breast Cancer without Previous Cardiac Disease—A Meta-Analysis
por: Mincu, Raluca I., et al.
Publicado: (2021)

Cardiac dysfunction from cancer and cancer therapy: new pathways for the prevention of late cardiotoxicity
por: Michel, Lars, et al.
Publicado: (2021)

Platinum-Based Drugs Cause Mitochondrial Dysfunction in Cultured Dorsal Root Ganglion Neurons
por: Leo, Markus, et al.
Publicado: (2020)

Blockade of ß-Adrenergic Receptors by Nebivolol Enables Tumor Control Potential for Uveal Melanoma in 3D Tumor Spheroids and 2D Cultures
por: Farhoumand, Lina S., et al.
Publicado: (2023)

Pulsed electron avalanche knife (PEAK) PlasmaBlade™ in pacemaker and defibrillator procedures
por: Kaya, Elif, et al.
Publicado: (2017)

Malaise and fatigue following mitral valve repair: case report
por: Hinrichs, Lena, et al.
Publicado: (2018)

Cardiotoxicity from chimeric antigen receptor-T cell therapy for advanced malignancies
por: Totzeck, Matthias, et al.
Publicado: (2022)

9-PAHSA Prevents Mitochondrial Dysfunction and Increases the Viability of Steatotic Hepatocytes
por: Schultz Moreira, Adriana R., et al.
Publicado: (2020)

The Adrenergic Receptor Antagonist Carvedilol Elicits Anti-Tumor Responses in Uveal Melanoma 3D Tumor Spheroids and May Serve as Co-Adjuvant Therapy with Radiation
por: Farhoumand, Lina S., et al.
Publicado: (2022)

Ticagrelor Leads to Statin-Induced Rhabdomyolysis: A Case Report
por: Mrotzek, Simone M., et al.
Publicado: (2017)

Cardiovascular Adverse Events in Patients With Cancer Treated With Bevacizumab: A Meta‐Analysis of More Than 20 000 Patients
por: Totzeck, Matthias, et al.
Publicado: (2017)

Cardiovascular Damage Associated With Chest Irradiation
por: Mrotzek, Simone M., et al.
Publicado: (2020)

S-nitrosation of mitochondrial connexin 43 regulates mitochondrial function
por: Soetkamp, Daniel, et al.
Publicado: (2014)

Heart failure from cancer therapy: can we prevent it?
por: Totzeck, Matthias, et al.
Publicado: (2019)

Unexpected high level of severe events even in low-risk profile chest pain unit patients
por: Breuckmann, Frank, et al.
Publicado: (2021)

Novel anticoagulants versus vitamin K antagonists for cardioversion of non- valvular atrial fibrillation – a meta-analysis of more than 17000 patients
por: Mincu, Raluca Ileana, et al.
Publicado: (2019)

Preprocedural C-Reactive Protein Predicts Outcomes after Primary Percutaneous Coronary Intervention in Patients with ST-elevation Myocardial Infarction a systematic meta-analysis
por: Mincu, Raluca-Ileana, et al.
Publicado: (2017)

Diagnostic Work-Up of Pulmonary Hypertension – Think About Shunt Flow! A Case Report
por: Hinrichs, Lena, et al.
Publicado: (2019)

Cardiopulmonary Profiling of Athletes with Post-Exertional Malaise after COVID-19 Infection—A Single-Center Experience
por: Wernhart, Simon, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_glqbhbb53jgbpm8kn1shqbkthq