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MPEP Attenuates Intrahepatic Fat Accumulation in Obese Mice

The blockade of metabotropic glutamate receptor type 5 (mGluR5) was previously found to reduce fat accumulation in HEPG2 cells. Here, we evaluated the effects of mGluR5 blockade in a mouse model of steatosis. Male ob/ob mice fed a high-fat diet were treated with MPEP or vehicle. After 7 weeks, liver...

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Detalles Bibliográficos
Autores principales:	Ferrigno, Andrea, Cagna, Marta, Bosco, Oriana, Trucchi, Michelangelo, Berardo, Clarissa, Nicoletti, Ferdinando, Vairetti, Mariapia, Di Pasqua, Laura G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094379/ https://www.ncbi.nlm.nih.gov/pubmed/37047048 http://dx.doi.org/10.3390/ijms24076076

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