Cargando…
Investigation of the Entry Pathway and Molecular Nature of σ1 Receptor Ligands
The σ1 receptor (σ1-R) is an enigmatic endoplasmic reticulum resident transmembrane protein implicated in a variety of central nervous system disorders and whose agonists have neuroprotective activity. In spite of σ1-R’s physio-pathological and pharmacological importance, two of the most important f...
Autores principales: | Pascarella, Gianmarco, Antonelli, Lorenzo, Narzi, Daniele, Battista, Theo, Fiorillo, Annarita, Colotti, Gianni, Guidoni, Leonardo, Morea, Veronica, Ilari, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094450/ https://www.ncbi.nlm.nih.gov/pubmed/37047338 http://dx.doi.org/10.3390/ijms24076367 |
Ejemplares similares
-
Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin
por: Fiorillo, Annarita, et al.
Publicado: (2021) -
Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases
por: Battista, Theo, et al.
Publicado: (2020) -
Known Drugs Identified by Structure-Based Virtual Screening Are Able to Bind Sigma-1 Receptor and Increase Growth of Huntington Disease Patient-Derived Cells
por: Battista, Theo, et al.
Publicado: (2021) -
Roles of Sorcin in Drug Resistance in Cancer: One Protein, Many Mechanisms, for a Novel Potential Anticancer Drug Target
por: Battista, Theo, et al.
Publicado: (2020) -
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy
por: Carbo, Miriam, et al.
Publicado: (2019)