Cargando…

Genetic Evidence for Endolysosomal Dysfunction in Parkinson’s Disease: A Critical Overview

Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the aging population, and no disease-modifying therapy has been approved to date. The pathogenesis of PD has been related to many dysfunctional cellular mechanisms, however, most of its monogenic forms are caused by pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yahya, Vidal, Di Fonzo, Alessio, Monfrini, Edoardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094484/ https://www.ncbi.nlm.nih.gov/pubmed/37047309 http://dx.doi.org/10.3390/ijms24076338

Ejemplares similares

Chorea‐Acanthocytosis Presenting with Parkinsonism‐Dystonia without Chorea
por: Monfrini, Edoardo, et al.
Publicado: (2023)

A Practical Approach to Early-Onset Parkinsonism
por: Riboldi, Giulietta M., et al.
Publicado: (2022)

Recent Advances in the Treatment of Genetic Forms of Parkinson’s Disease: Hype or Hope?
por: Cavallieri, Francesco, et al.
Publicado: (2023)

LRRK2 and the Endolysosomal System in Parkinson’s Disease
por: Erb, Madalynn L., et al.
Publicado: (2020)

GBA, Gaucher Disease, and Parkinson’s Disease: From Genetic to Clinic to New Therapeutic Approaches
por: Riboldi, Giulietta M., et al.
Publicado: (2019)

Alpha-Synuclein and the Endolysosomal System in Parkinson’s Disease: Guilty by Association
por: Teixeira, Maxime, et al.
Publicado: (2021)

Unravelling Genetic Factors Underlying Corticobasal Syndrome: A Systematic Review
por: Arienti, Federica, et al.
Publicado: (2021)

The critical role of the endolysosomal system in cerebral ischemia
por: Zhang, Hui-Yi, et al.
Publicado: (2022)

Clinical uses of Bupropion in patients with Parkinson’s disease and comorbid depressive or neuropsychiatric symptoms: a scoping review
por: Vismara, Matteo, et al.
Publicado: (2022)

Endolysosomal dysfunction and exosome secretion: implications for neurodegenerative disorders
por: Miranda, André M., et al.
Publicado: (2018)

The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson’s disease
por: Smith, Jessica K., et al.
Publicado: (2023)

Endolysosomal Cation Channels and Lung Disease
por: Spix, Barbara, et al.
Publicado: (2022)

Endolysosomal TRPMLs in Cancer
por: Xu, Mengnan, et al.
Publicado: (2021)

Age-related endolysosome dysfunction in the rat urothelium
por: Truschel, Steven T., et al.
Publicado: (2018)

LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson’s disease
por: Rocha, Emily M., et al.
Publicado: (2019)

Dysautonomia in Parkinson’s Disease: Impact of Glucocerebrosidase Gene Mutations on Cardiovascular Autonomic Control
por: Carandina, Angelica, et al.
Publicado: (2022)

Endolysosome and Autolysosome Dysfunction in Alzheimer’s Disease: Where Intracellular and Extracellular Meet
por: van Weering, Jan R. T., et al.
Publicado: (2019)

Dysfunctional Autophagy and Endolysosomal System in Neurodegenerative Diseases: Relevance and Therapeutic Options
por: Giovedì, Silvia, et al.
Publicado: (2020)

Microscopic Polyangiitis With Selective Involvement of Central and Peripheral Nervous System: A Case Report
por: Arienti, Federica, et al.
Publicado: (2020)

Animal secretory endolysosome channel discovery
por: Zhang, Yun, et al.
Publicado: (2021)

Autophagy and the endolysosomal system in presynaptic function
por: Andres-Alonso, Maria, et al.
Publicado: (2020)

Role of Lysosomal Gene Variants in Modulating GBA ‐Associated Parkinson's Disease Risk
por: Straniero, Letizia, et al.
Publicado: (2022)

Anderson–Fabry Disease: A New Piece of the Lysosomal Puzzle in Parkinson Disease?
por: Zedde, Marialuisa, et al.
Publicado: (2022)

Ubiquitin and its relatives as wizards of the endolysosomal system
por: Berlin, Ilana, et al.
Publicado: (2023)

The Swing of Lipids at Peroxisomes and Endolysosomes in T Cell Activation
por: Dosil, Sara G., et al.
Publicado: (2020)

Endolysosomal Cation Channels and MITF in Melanocytes and Melanoma
por: Abrahamian, Carla, et al.
Publicado: (2021)

Tremulous spastic ataxia in a patient with a homozygous truncating SYNE1 variant
por: Spagnolo, Francesca, et al.
Publicado: (2023)

The genetic architecture of mitochondrial dysfunction in Parkinson’s disease
por: Larsen, S. B., et al.
Publicado: (2018)

Bright Light Therapy in Parkinson's Disease: An Overview of the Background and Evidence
por: Rutten, Sonja, et al.
Publicado: (2012)

Neuronal endolysosomal transport and lysosomal functionality in maintaining axonostasis
por: Roney, Joseph C., et al.
Publicado: (2022)

TWNK in Parkinson's Disease: A Movement Disorder and Mitochondrial Disease Center Perspective Study
por: Percetti, Marco, et al.
Publicado: (2022)

Hyperactivated endolysosomal trafficking in melanoma
por: Alonso-Curbelo, Direna, et al.
Publicado: (2015)

Inter-organelle ER-endolysosomal contact sites in metabolism and disease across evolution
por: Hariri, Hanaa, et al.
Publicado: (2016)

Brain Calcifications: Genetic, Molecular, and Clinical Aspects
por: Monfrini, Edoardo, et al.
Publicado: (2023)

A dysfunctional endolysosomal pathway common to two sub-types of demyelinating Charcot–Marie–Tooth disease
por: Edgar, James R., et al.
Publicado: (2020)

Endolysosomal Cation Channels and Cancer—A Link with Great Potential
por: Grimm, Christian, et al.
Publicado: (2018)

Current Knowledge of Endolysosomal and Autophagy Defects in Hereditary Spastic Paraplegia
por: Toupenet Marchesi, Liriopé, et al.
Publicado: (2021)

The Endolysosomal System: The Acid Test for SARS-CoV-2
por: Cesar-Silva, Daniella, et al.
Publicado: (2022)

Electrophysiology of Endolysosomal Two-Pore Channels: A Current Account
por: Patel, Sandip, et al.
Publicado: (2022)

The role of Alzheimer’s disease risk genes in endolysosomal pathways
por: Szabo, Marcell P., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vhtokd82rbacurbhjh51dkcvjo