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N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants

N-type voltage-gated calcium channel controls the release of neurotransmitters from neurons. The association of other voltage-gated calcium channels with epilepsy is well-known. The association of N-type voltage-gated calcium channels and pain has also been established. However, the relationship bet...

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Autores principales: Mayo, Sonia, Gómez-Manjón, Irene, Marco-Hernández, Ana Victoria, Fernández-Martínez, Francisco Javier, Camacho, Ana, Martínez, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094502/
https://www.ncbi.nlm.nih.gov/pubmed/37047073
http://dx.doi.org/10.3390/ijms24076100
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author Mayo, Sonia
Gómez-Manjón, Irene
Marco-Hernández, Ana Victoria
Fernández-Martínez, Francisco Javier
Camacho, Ana
Martínez, Francisco
author_facet Mayo, Sonia
Gómez-Manjón, Irene
Marco-Hernández, Ana Victoria
Fernández-Martínez, Francisco Javier
Camacho, Ana
Martínez, Francisco
author_sort Mayo, Sonia
collection PubMed
description N-type voltage-gated calcium channel controls the release of neurotransmitters from neurons. The association of other voltage-gated calcium channels with epilepsy is well-known. The association of N-type voltage-gated calcium channels and pain has also been established. However, the relationship between this type of calcium channel and epilepsy has not been specifically reviewed. Therefore, the present review systematically summarizes existing publications regarding the genetic associations between N-type voltage-dependent calcium channel and epilepsy.
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spelling pubmed-100945022023-04-13 N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants Mayo, Sonia Gómez-Manjón, Irene Marco-Hernández, Ana Victoria Fernández-Martínez, Francisco Javier Camacho, Ana Martínez, Francisco Int J Mol Sci Review N-type voltage-gated calcium channel controls the release of neurotransmitters from neurons. The association of other voltage-gated calcium channels with epilepsy is well-known. The association of N-type voltage-gated calcium channels and pain has also been established. However, the relationship between this type of calcium channel and epilepsy has not been specifically reviewed. Therefore, the present review systematically summarizes existing publications regarding the genetic associations between N-type voltage-dependent calcium channel and epilepsy. MDPI 2023-03-23 /pmc/articles/PMC10094502/ /pubmed/37047073 http://dx.doi.org/10.3390/ijms24076100 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mayo, Sonia
Gómez-Manjón, Irene
Marco-Hernández, Ana Victoria
Fernández-Martínez, Francisco Javier
Camacho, Ana
Martínez, Francisco
N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants
title N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants
title_full N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants
title_fullStr N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants
title_full_unstemmed N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants
title_short N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants
title_sort n-type ca channel in epileptic syndromes and epilepsy: a systematic review of its genetic variants
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094502/
https://www.ncbi.nlm.nih.gov/pubmed/37047073
http://dx.doi.org/10.3390/ijms24076100
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