Fatty Acid Induced Hypermethylation in the Slc2a4 Gene in Visceral Adipose Tissue Is Associated to Insulin-Resistance and Obesity

De novo lipogenesis (DNL) in visceral adipose tissue (VAT) is associated with systemic insulin sensitivity. DNL in VAT is regulated through ChREBP activity and glucose uptake through Glut4 (encoded by Slc2a4). Slc2a4 expression, ChREBP activity, and DNL are decreased in obesity, the underlying cause...

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Detalles Bibliográficos
Autores principales: Britsemmer, Jan H., Krause, Christin, Taege, Natalie, Geißler, Cathleen, Lopez-Alcantara, Nuria, Schmidtke, Linda, Naujack, Alison-Michelle, Wagner, Jonas, Wolter, Stefan, Mann, Oliver, Kirchner, Henriette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094548/
https://www.ncbi.nlm.nih.gov/pubmed/37047391
http://dx.doi.org/10.3390/ijms24076417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094548/
https://www.ncbi.nlm.nih.gov/pubmed/37047391
http://dx.doi.org/10.3390/ijms24076417

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