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A Novel Cu(2+) Quantitative Detection Nucleic Acid Biosensors Based on DNAzyme and “Blocker” Beacon

In this paper, a “turn-off” biosensor for detecting copper (II) ions based on Cu(2+)-dependent DNAzyme and a “blocker” beacon were developed. Upon the copper ion being added, the Cu(2+)-dependent DNAzyme substrate strand was irreversibly cleaved, thereby blocking the occurrence of the ligation react...

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Detalles Bibliográficos
Autores principales: Zhang, Hanyue, Dong, Kai, Xiang, Shuna, Lin, Yingting, Cha, Xiaoyan, Shang, Ying, Xu, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094606/
https://www.ncbi.nlm.nih.gov/pubmed/37048325
http://dx.doi.org/10.3390/foods12071504