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A Novel Cu(2+) Quantitative Detection Nucleic Acid Biosensors Based on DNAzyme and “Blocker” Beacon
In this paper, a “turn-off” biosensor for detecting copper (II) ions based on Cu(2+)-dependent DNAzyme and a “blocker” beacon were developed. Upon the copper ion being added, the Cu(2+)-dependent DNAzyme substrate strand was irreversibly cleaved, thereby blocking the occurrence of the ligation react...
Autores principales: | Zhang, Hanyue, Dong, Kai, Xiang, Shuna, Lin, Yingting, Cha, Xiaoyan, Shang, Ying, Xu, Wentao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094606/ https://www.ncbi.nlm.nih.gov/pubmed/37048325 http://dx.doi.org/10.3390/foods12071504 |
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