Cargando…

The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study

Background: Little is known about the influence of the duration of the kidney back-table preparation period and kidney temperature on graft outcomes after transplantation. The aim of this study is to investigate the back-table duration and its relation to graft outcome and the relation between kidne...

Descripción completa

Detalles Bibliográficos
Autores principales: Slagter, Julia S., Rijkse, Elsaline, De Wilde, Roeland F., Haen, Roel, Lepiesza, Agnieszka, Cappelle, Marie L., Kimenai, Diederik H. J. A. N., Minnee, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094751/
https://www.ncbi.nlm.nih.gov/pubmed/37048729
http://dx.doi.org/10.3390/jcm12072647
_version_ 1785023916059656192
author Slagter, Julia S.
Rijkse, Elsaline
De Wilde, Roeland F.
Haen, Roel
Lepiesza, Agnieszka
Cappelle, Marie L.
Kimenai, Diederik H. J. A. N.
Minnee, Robert C.
author_facet Slagter, Julia S.
Rijkse, Elsaline
De Wilde, Roeland F.
Haen, Roel
Lepiesza, Agnieszka
Cappelle, Marie L.
Kimenai, Diederik H. J. A. N.
Minnee, Robert C.
author_sort Slagter, Julia S.
collection PubMed
description Background: Little is known about the influence of the duration of the kidney back-table preparation period and kidney temperature on graft outcomes after transplantation. The aim of this study is to investigate the back-table duration and its relation to graft outcome and the relation between kidney temperature and graft outcome. Methods: In this prospective cohort study, deceased donor kidney temperature is measured at fixed time points using an infrared thermometer during back-table preparation and transplantation. Additionally, the back-table duration is measured using a timer. Results: Between September 2020 and July 2021, 49 kidneys were prospectively included in this study. Median back-table duration was 33.7 (standard deviation ± 14.1) min and donor kidney temperature increased up to 14.9 °C (±2.8) after 60 min of back-table preparation. Mean implantation time was 24.9 (±7.6) min and kidney temperature increased up to 25.9 °C (±2.4) after 30 min of implantation time. Longer back-table duration was significantly associated with higher rates of delayed graft function (p = 0.037). However, this observation did not sustain at 3 and 6-months post-transplantation. No association was found between kidney temperature and graft outcomes. Conclusion: Longer back-table duration is significantly associated with DGF after deceased donor kidney transplantation. No association was observed between kidney temperature and graft outcomes of deceased donor kidneys.
format Online
Article
Text
id pubmed-10094751
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100947512023-04-13 The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study Slagter, Julia S. Rijkse, Elsaline De Wilde, Roeland F. Haen, Roel Lepiesza, Agnieszka Cappelle, Marie L. Kimenai, Diederik H. J. A. N. Minnee, Robert C. J Clin Med Article Background: Little is known about the influence of the duration of the kidney back-table preparation period and kidney temperature on graft outcomes after transplantation. The aim of this study is to investigate the back-table duration and its relation to graft outcome and the relation between kidney temperature and graft outcome. Methods: In this prospective cohort study, deceased donor kidney temperature is measured at fixed time points using an infrared thermometer during back-table preparation and transplantation. Additionally, the back-table duration is measured using a timer. Results: Between September 2020 and July 2021, 49 kidneys were prospectively included in this study. Median back-table duration was 33.7 (standard deviation ± 14.1) min and donor kidney temperature increased up to 14.9 °C (±2.8) after 60 min of back-table preparation. Mean implantation time was 24.9 (±7.6) min and kidney temperature increased up to 25.9 °C (±2.4) after 30 min of implantation time. Longer back-table duration was significantly associated with higher rates of delayed graft function (p = 0.037). However, this observation did not sustain at 3 and 6-months post-transplantation. No association was found between kidney temperature and graft outcomes. Conclusion: Longer back-table duration is significantly associated with DGF after deceased donor kidney transplantation. No association was observed between kidney temperature and graft outcomes of deceased donor kidneys. MDPI 2023-04-02 /pmc/articles/PMC10094751/ /pubmed/37048729 http://dx.doi.org/10.3390/jcm12072647 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Slagter, Julia S.
Rijkse, Elsaline
De Wilde, Roeland F.
Haen, Roel
Lepiesza, Agnieszka
Cappelle, Marie L.
Kimenai, Diederik H. J. A. N.
Minnee, Robert C.
The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study
title The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study
title_full The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study
title_fullStr The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study
title_full_unstemmed The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study
title_short The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study
title_sort effect of recipient back-table duration on graft outcome of deceased donor kidneys: a single-center prospective cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094751/
https://www.ncbi.nlm.nih.gov/pubmed/37048729
http://dx.doi.org/10.3390/jcm12072647
work_keys_str_mv AT slagterjulias theeffectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT rijkseelsaline theeffectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT dewilderoelandf theeffectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT haenroel theeffectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT lepieszaagnieszka theeffectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT cappellemariel theeffectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT kimenaidiederikhjan theeffectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT minneerobertc theeffectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT slagterjulias effectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT rijkseelsaline effectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT dewilderoelandf effectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT haenroel effectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT lepieszaagnieszka effectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT cappellemariel effectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT kimenaidiederikhjan effectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy
AT minneerobertc effectofrecipientbacktabledurationongraftoutcomeofdeceaseddonorkidneysasinglecenterprospectivecohortstudy