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Neonatal Exposure to Valproate Induces Long-Term Alterations in Steroid Hormone Levels in the Brain Cortex of Prepubertal Rats

Valproic acid (VPA) is a known drug for treating epilepsy and mood disorders; however, it is not recommended for pregnant women because of its possible teratogenicity. VPA affects neurotransmission and gene expression through epigenetic mechanisms by acting as a histone deacetylase inhibitor and has...

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Detalles Bibliográficos
Autores principales: Kim, Soon-Ae, Jang, Eun-Hye, Lee, Jangjae, Cho, Sung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094755/
https://www.ncbi.nlm.nih.gov/pubmed/37047656
http://dx.doi.org/10.3390/ijms24076681