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Neonatal Exposure to Valproate Induces Long-Term Alterations in Steroid Hormone Levels in the Brain Cortex of Prepubertal Rats
Valproic acid (VPA) is a known drug for treating epilepsy and mood disorders; however, it is not recommended for pregnant women because of its possible teratogenicity. VPA affects neurotransmission and gene expression through epigenetic mechanisms by acting as a histone deacetylase inhibitor and has...
Autores principales: | Kim, Soon-Ae, Jang, Eun-Hye, Lee, Jangjae, Cho, Sung-Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094755/ https://www.ncbi.nlm.nih.gov/pubmed/37047656 http://dx.doi.org/10.3390/ijms24076681 |
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