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Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan

COVID-19 is a public health crisis that has caused numerous deaths, necessitated an increased number of hospital admissions, and led to extended inpatient stays. This study aimed to identify the factors associated with COVID-19 mortality, intensive care unit admission, intubation, and length of hosp...

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Autores principales: Al Oweidat, Khaled, Al-Amer, Rasmieh, Saleh, Mohammad Y., Albtoosh, Asma S., Toubasi, Ahmad A., Ribie, Mona Khaled, Hasuneh, Manar M., Alfaqheri, Daniah L., Alshurafa, Abdullah H., Ribie, Mohammad, Ali, Amira Mohammed, Obeidat, Nathir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094820/
https://www.ncbi.nlm.nih.gov/pubmed/37048734
http://dx.doi.org/10.3390/jcm12072651
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author Al Oweidat, Khaled
Al-Amer, Rasmieh
Saleh, Mohammad Y.
Albtoosh, Asma S.
Toubasi, Ahmad A.
Ribie, Mona Khaled
Hasuneh, Manar M.
Alfaqheri, Daniah L.
Alshurafa, Abdullah H.
Ribie, Mohammad
Ali, Amira Mohammed
Obeidat, Nathir
author_facet Al Oweidat, Khaled
Al-Amer, Rasmieh
Saleh, Mohammad Y.
Albtoosh, Asma S.
Toubasi, Ahmad A.
Ribie, Mona Khaled
Hasuneh, Manar M.
Alfaqheri, Daniah L.
Alshurafa, Abdullah H.
Ribie, Mohammad
Ali, Amira Mohammed
Obeidat, Nathir
author_sort Al Oweidat, Khaled
collection PubMed
description COVID-19 is a public health crisis that has caused numerous deaths, necessitated an increased number of hospital admissions, and led to extended inpatient stays. This study aimed to identify the factors associated with COVID-19 mortality, intensive care unit admission, intubation, and length of hospital stay among Jordanian patients. This was a one-year retrospective study of 745 COVID-19 patients admitted to Jordan University Hospital. Data regarding the patients’ demographics, clinical and co-morbid conditions, imaging, laboratory parameters, mortality, intensive care unit admission (ICU), and intubation were collected from their medical records using a coding manual. The data revealed that the overall rates of COVID-19-related mortality, ICU admission, and invasive intubation were 23.0%, 28.3%, and 10.8%, respectively. Chronic kidney disease (CKD), troponin, lactate dehydrogenase (LDH), and O(2) saturation <90% were significantly associated with the mortality rate. The variables that were significantly associated with ICU admission were heart failure and the use of remdesivir. However, O(2) saturation <90% and gastrointestinal (GI) symptoms were the only variables associated with invasive intubation. The findings of this study suggest that study-related health outcomes can be used to predict the severity of COVID-19, and they can inform future research aiming to identify specific populations who are at a higher risk of COVID-19 complications.
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spelling pubmed-100948202023-04-13 Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan Al Oweidat, Khaled Al-Amer, Rasmieh Saleh, Mohammad Y. Albtoosh, Asma S. Toubasi, Ahmad A. Ribie, Mona Khaled Hasuneh, Manar M. Alfaqheri, Daniah L. Alshurafa, Abdullah H. Ribie, Mohammad Ali, Amira Mohammed Obeidat, Nathir J Clin Med Article COVID-19 is a public health crisis that has caused numerous deaths, necessitated an increased number of hospital admissions, and led to extended inpatient stays. This study aimed to identify the factors associated with COVID-19 mortality, intensive care unit admission, intubation, and length of hospital stay among Jordanian patients. This was a one-year retrospective study of 745 COVID-19 patients admitted to Jordan University Hospital. Data regarding the patients’ demographics, clinical and co-morbid conditions, imaging, laboratory parameters, mortality, intensive care unit admission (ICU), and intubation were collected from their medical records using a coding manual. The data revealed that the overall rates of COVID-19-related mortality, ICU admission, and invasive intubation were 23.0%, 28.3%, and 10.8%, respectively. Chronic kidney disease (CKD), troponin, lactate dehydrogenase (LDH), and O(2) saturation <90% were significantly associated with the mortality rate. The variables that were significantly associated with ICU admission were heart failure and the use of remdesivir. However, O(2) saturation <90% and gastrointestinal (GI) symptoms were the only variables associated with invasive intubation. The findings of this study suggest that study-related health outcomes can be used to predict the severity of COVID-19, and they can inform future research aiming to identify specific populations who are at a higher risk of COVID-19 complications. MDPI 2023-04-02 /pmc/articles/PMC10094820/ /pubmed/37048734 http://dx.doi.org/10.3390/jcm12072651 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al Oweidat, Khaled
Al-Amer, Rasmieh
Saleh, Mohammad Y.
Albtoosh, Asma S.
Toubasi, Ahmad A.
Ribie, Mona Khaled
Hasuneh, Manar M.
Alfaqheri, Daniah L.
Alshurafa, Abdullah H.
Ribie, Mohammad
Ali, Amira Mohammed
Obeidat, Nathir
Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan
title Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan
title_full Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan
title_fullStr Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan
title_full_unstemmed Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan
title_short Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan
title_sort mortality, intensive care unit admission, and intubation among hospitalized patients with covid-19: a one-year retrospective study in jordan
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094820/
https://www.ncbi.nlm.nih.gov/pubmed/37048734
http://dx.doi.org/10.3390/jcm12072651
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