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Physiological and Functional Effects of Dominant Active TCRα Expression in Transgenic Mice

A T cell receptor (TCR) consists of α- and β-chains. Accumulating evidence suggests that some TCRs possess chain centricity, i.e., either of the hemi-chains can dominate in antigen recognition and dictate the TCR’s specificity. The introduction of TCRα/β into naive lymphocytes generates antigen-spec...

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Detalles Bibliográficos
Autores principales:	Kalinina, Anastasiia A., Ziganshin, Rustam Kh., Silaeva, Yulia Yu., Sharova, Nina I., Nikonova, Margarita F., Persiyantseva, Nadezda A., Gorkova, Tatiana G., Antoshina, Elena E., Trukhanova, Lubov S., Donetskova, Almira D., Komogorova, Victoria V., Litvina, Marina M., Mitin, Alexander N., Zamkova, Maria A., Bruter, Alexandra V., Khromykh, Ludmila M., Kazansky, Dmitry B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094918/ https://www.ncbi.nlm.nih.gov/pubmed/37047500 http://dx.doi.org/10.3390/ijms24076527

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