Cargando…
Exploring the Pathological Effect of Aβ42 Oligomers on Neural Networks in Primary Cortical Neuron Culture
Alzheimer’s disease (AD) is a multifactorial disorder that affects cognitive functioning, behavior, and neuronal properties. The neuronal dysfunction is primarily responsible for cognitive decline in AD patients, with many causal factors including plaque accumulation of Aβ42. Neural hyperactivity in...
Autores principales: | Ganbat, Dulguun, Jeon, Jae Kyong, Lee, Yunjong, Kim, Sang Seong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094920/ https://www.ncbi.nlm.nih.gov/pubmed/37047612 http://dx.doi.org/10.3390/ijms24076641 |
Ejemplares similares
-
Alteration of Neural Network and Hippocampal Slice Activation through Exosomes Derived from 5XFAD Nasal Lavage Fluid
por: Kim, Sangseong, et al.
Publicado: (2023) -
The Antioxidant Activity of Limonene Counteracts Neurotoxicity Triggered byAβ(1-42) Oligomers in Primary Cortical Neurons
por: Piccialli, Ilaria, et al.
Publicado: (2021) -
MEK1/2 inhibition rescues neurodegeneration by TFEB-mediated activation of autophagic lysosomal function in a model of Alzheimer’s Disease
por: Chun, Yoon Sun, et al.
Publicado: (2022) -
Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers I: Abeta 42 Oligomer Binding to Specific Neuronal Receptors Is Displaced by Drug Candidates That Improve Cognitive Deficits
por: Izzo, Nicholas J., et al.
Publicado: (2014) -
Capping of Aβ42 Oligomers by Small Molecule
Inhibitors
por: Fu, Ziao, et al.
Publicado: (2014)