Cargando…

Lung Epithelial Cells from Obese Patients Have Impaired Control of SARS-CoV-2 Infection

Obesity is known to increase the complications of the COVID-19 coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the exact mechanisms of SARS-CoV-2 infection in obese patients have not been clearly elucidated. This study aims to better understand th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gaudet, Mellissa, Kaufmann, Eva, Jalaleddine, Nour, Mogas, Andrea, Hachim, Mahmood, Senok, Abiola, Divangahi, Maziar, Hamid, Qutayba, Al Heialy, Saba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095048/ https://www.ncbi.nlm.nih.gov/pubmed/37047702 http://dx.doi.org/10.3390/ijms24076729

Ejemplares similares

Recent advances in vitamin D implications in chronic respiratory diseases
por: Gaudet, Mellissa, et al.
Publicado: (2022)

Vitamin D3 Attenuates Viral-Induced Inflammation and Fibrotic Responses in Bronchial Smooth Muscle Cells
por: Plesa, Maria, et al.
Publicado: (2021)

Regulation of Angiotensin- Converting Enzyme 2 in Obesity: Implications for COVID-19
por: Al Heialy, Saba, et al.
Publicado: (2020)

Simulated Microgravity Influences Immunity-Related Biomarkers in Lung Cancer
por: Baghoum, Hend, et al.
Publicado: (2022)

Molecular Basis of Cardiac and Vascular Injuries Associated With COVID-19
por: Hachim, Mahmood Yaseen, et al.
Publicado: (2020)

Interferon-Induced Transmembrane Protein (IFITM3) Is Upregulated Explicitly in SARS-CoV-2 Infected Lung Epithelial Cells
por: Hachim, Mahmood Yaseen, et al.
Publicado: (2020)

ACE2 polymorphisms impact COVID-19 severity in obese patients
por: Jalaleddine, Nour, et al.
Publicado: (2022)

Contribution of IL-17 in Steroid Hyporesponsiveness in Obese Asthmatics Through Dysregulation of Glucocorticoid Receptors α and β
por: Al Heialy, Saba, et al.
Publicado: (2020)

Action of 1,25(OH)(2)D(3) on Human Asthmatic Bronchial Fibroblasts: Implications for Airway Remodeling in Asthma
por: Plesa, Maria, et al.
Publicado: (2020)

N6-Acetyl-L-Lysine and p-Cresol as Key Metabolites in the Pathogenesis of COVID-19 in Obese Patients
por: Jalaleddine, Nour, et al.
Publicado: (2022)

The Role of Systems Biology in Deciphering Asthma Heterogeneity
por: Hachim, Mahmood Yaseen, et al.
Publicado: (2022)

Neutrophils from severe asthmatic patients induce epithelial to mesenchymal transition in healthy bronchial epithelial cells
por: Haddad, Alexandre, et al.
Publicado: (2019)

Novel Markers in Pediatric Acute Lymphoid Leukemia: The Role of ADAM6 in B Cell Leukemia
por: Alsuwaidi, Laila, et al.
Publicado: (2021)

COVID-19 Transcriptomic Atlas: A Comprehensive Analysis of COVID-19 Related Transcriptomics Datasets
por: Alqutami, Fatma, et al.
Publicado: (2021)

The Molecular Basis of Gender Variations in Mortality Rates Associated With the Novel Coronavirus (COVID-19) Outbreak
por: Hachim, Ibrahim Y., et al.
Publicado: (2021)

Confounding Patient Factors Affecting the Proper Interpretation of the Periostin Level as a Biomarker in Asthma Development
por: Hachim, Mahmood Yaseen, et al.
Publicado: (2020)

Wnt Signaling Is Deranged in Asthmatic Bronchial Epithelium and Fibroblasts
por: Hachim, Mahmood Yaseen, et al.
Publicado: (2021)

Author Correction: Derangement of cell cycle markers in peripheral blood mononuclear cells of asthmatic patients as a reliable biomarker for asthma control
por: Hachim, Mahmood Yaseen, et al.
Publicado: (2021)

Derangement of cell cycle markers in peripheral blood mononuclear cells of asthmatic patients as a reliable biomarker for asthma control
por: Hachim, Mahmood Yaseen, et al.
Publicado: (2021)

Blood and Salivary Amphiregulin Levels as Biomarkers for Asthma
por: Hachim, Mahmood Yaseen, et al.
Publicado: (2020)

Combination of obesity and co-morbidities leads to unfavorable outcomes in COVID-19 patients
por: Al Heialy, Saba, et al.
Publicado: (2021)

Shaping the future-ready doctor: a first-aid kit to address a gap in medical education
por: Otaki, Farah, et al.
Publicado: (2020)

Beyond Killing Mycobacterium tuberculosis: Disease Tolerance
por: Divangahi, Maziar, et al.
Publicado: (2018)

IL-17 Induced Autophagy Regulates Mitochondrial Dysfunction and Fibrosis in Severe Asthmatic Bronchial Fibroblasts
por: Ramakrishnan, Rakhee K., et al.
Publicado: (2020)

Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients
por: Ramakrishnan, Rakhee K., et al.
Publicado: (2020)

Effect of Common Medications on the Expression of SARS‐CoV‐2 Entry Receptors in Kidney Tissue
por: Saheb Sharif‐Askari, Narjes, et al.
Publicado: (2020)

Unravelling the networks dictating host resistance versus tolerance during pulmonary infections
por: Meunier, Isabelle, et al.
Publicado: (2017)

Microbial Metabolic Genes Crucial for S. aureus Biofilms: An Insight From Re-analysis of Publicly Available Microarray Datasets
por: Nassar, Rania, et al.
Publicado: (2021)

EXOC6 (Exocyst Complex Component 6) Is Associated with the Risk of Type 2 Diabetes and Pancreatic β-Cell Dysfunction
por: Sulaiman, Nabil, et al.
Publicado: (2022)

Monocyte distribution width as a novel sepsis indicator in COVID-19 patients
por: Alsuwaidi, Laila, et al.
Publicado: (2022)

Asthma Associated Cytokines Regulate the Expression of SARS-CoV-2 Receptor ACE2 in the Lung Tissue of Asthmatic Patients
por: Saheb Sharif-Askari, Fatemeh, et al.
Publicado: (2022)

Efferocytosis: Burying cell corpses to regulate tolerance and immunity
por: Divangahi, Maziar
Publicado: (2015)

Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients
por: Nishioka, Michiyoshi, et al.
Publicado: (2015)

Vitamin D Regulates the Expression of Glucocorticoid Receptors in Blood of Severe Asthmatic Patients
por: Mahboub, Bassam, et al.
Publicado: (2021)

Cardiovascular medications and regulation of COVID-19 receptors expression
por: Saheb Sharif-Askari, Narjes, et al.
Publicado: (2020)

Airways Expression of SARS-CoV-2 Receptor, ACE2, and TMPRSS2 Is Lower in Children Than Adults and Increases with Smoking and COPD
por: Saheb Sharif-Askari, Narjes, et al.
Publicado: (2020)

Asthma severity as a contributing factor to cancer incidence: A cohort study
por: Salameh, Laila, et al.
Publicado: (2021)

Probiotics in the Arabian Gulf Region
por: Senok, Abiola C.
Publicado: (2009)

Enhanced expression of immune checkpoint receptors during SARS-CoV-2 viral infection
por: Saheb Sharif-Askari, Narjes, et al.
Publicado: (2020)

Analyzing single cell transcriptome data from severe COVID-19 patients
por: Nassir, Nasna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pebkd04mspuqu6vkv3mkamc8hd