Oncostatin M-Enriched Small Extracellular Vesicles Derived from Mesenchymal Stem Cells Prevent Isoproterenol-Induced Fibrosis and Enhance Angiogenesis

Myocardial fibrosis is a pathological hallmark of cardiac dysfunction. Oncostatin M (OSM) is a pleiotropic cytokine that can promote fibrosis in different organs after sustained exposure. However, OSM released by macrophages during cardiac fibrosis suppresses cardiac fibroblast activation by modulat...

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Detalles Bibliográficos
Autores principales: Tejedor, Sandra, Buigues, Marc, González-King, Hernán, Silva, Andreia M., García, Nahuel Aquiles, Dekker, Niek, Sepúlveda, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095085/
https://www.ncbi.nlm.nih.gov/pubmed/37047440
http://dx.doi.org/10.3390/ijms24076467

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