Cargando…

Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis

Effusion-synovitis (ES) is recognized as a component of osteoarthritis, creating a need for rapid methods to assess ES on MRI. We describe the development and reliability of an efficient single-slice semi-automated quantitative approach to measure ES. We used two samples from the Osteoarthritis Init...

Descripción completa

Detalles Bibliográficos
Autores principales: Gilles, Greg, Vohra, Arjun, Robles, Dagoberto, Taljanovic, Mihra S., Ashbeck, Erin L., Caruso, Chelsea, Duryea, Jeffrey, Bedrick, Edward J., Guermazi, Ali, Kwoh, C. Kent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095125/
https://www.ncbi.nlm.nih.gov/pubmed/37048775
http://dx.doi.org/10.3390/jcm12072691
_version_ 1785024007764967424
author Gilles, Greg
Vohra, Arjun
Robles, Dagoberto
Taljanovic, Mihra S.
Ashbeck, Erin L.
Caruso, Chelsea
Duryea, Jeffrey
Bedrick, Edward J.
Guermazi, Ali
Kwoh, C. Kent
author_facet Gilles, Greg
Vohra, Arjun
Robles, Dagoberto
Taljanovic, Mihra S.
Ashbeck, Erin L.
Caruso, Chelsea
Duryea, Jeffrey
Bedrick, Edward J.
Guermazi, Ali
Kwoh, C. Kent
author_sort Gilles, Greg
collection PubMed
description Effusion-synovitis (ES) is recognized as a component of osteoarthritis, creating a need for rapid methods to assess ES on MRI. We describe the development and reliability of an efficient single-slice semi-automated quantitative approach to measure ES. We used two samples from the Osteoarthritis Initiative (OAI): 50 randomly selected OAI participants with radiographic osteoarthritis (i.e., Kellgren–Lawrence (KL) grade 2 or 3) and a subset from the Foundation for the National Institutes of Health Osteoarthritis Biomarker study. An experienced musculoskeletal radiologist trained four non-expert readers to use custom semi-automated software to measure ES on a single axial slice and then read scans blinded to prior assessments. The estimated intraclass correlation coefficient (ICC) for intra-reader reliability of the single-slice ES method in the KL 2–3 sample was 0.96 (95% CI: 0.93, 0.97), and for inter-reader reliability, the ICC was 0.90 (95% CI: 0.87, 0.95). The intra-reader mean absolute difference (MAD) was 35 mm(3) (95% CI: 28, 44), and the inter-reader MAD was 61 mm(3) (95% CI: 48, 76). Our single-slice quantitative knee ES measurement offers a reliable, valid, and efficient surrogate for multi-slice quantitative and semi-quantitative assessment.
format Online
Article
Text
id pubmed-10095125
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100951252023-04-13 Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis Gilles, Greg Vohra, Arjun Robles, Dagoberto Taljanovic, Mihra S. Ashbeck, Erin L. Caruso, Chelsea Duryea, Jeffrey Bedrick, Edward J. Guermazi, Ali Kwoh, C. Kent J Clin Med Article Effusion-synovitis (ES) is recognized as a component of osteoarthritis, creating a need for rapid methods to assess ES on MRI. We describe the development and reliability of an efficient single-slice semi-automated quantitative approach to measure ES. We used two samples from the Osteoarthritis Initiative (OAI): 50 randomly selected OAI participants with radiographic osteoarthritis (i.e., Kellgren–Lawrence (KL) grade 2 or 3) and a subset from the Foundation for the National Institutes of Health Osteoarthritis Biomarker study. An experienced musculoskeletal radiologist trained four non-expert readers to use custom semi-automated software to measure ES on a single axial slice and then read scans blinded to prior assessments. The estimated intraclass correlation coefficient (ICC) for intra-reader reliability of the single-slice ES method in the KL 2–3 sample was 0.96 (95% CI: 0.93, 0.97), and for inter-reader reliability, the ICC was 0.90 (95% CI: 0.87, 0.95). The intra-reader mean absolute difference (MAD) was 35 mm(3) (95% CI: 28, 44), and the inter-reader MAD was 61 mm(3) (95% CI: 48, 76). Our single-slice quantitative knee ES measurement offers a reliable, valid, and efficient surrogate for multi-slice quantitative and semi-quantitative assessment. MDPI 2023-04-04 /pmc/articles/PMC10095125/ /pubmed/37048775 http://dx.doi.org/10.3390/jcm12072691 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gilles, Greg
Vohra, Arjun
Robles, Dagoberto
Taljanovic, Mihra S.
Ashbeck, Erin L.
Caruso, Chelsea
Duryea, Jeffrey
Bedrick, Edward J.
Guermazi, Ali
Kwoh, C. Kent
Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis
title Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis
title_full Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis
title_fullStr Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis
title_full_unstemmed Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis
title_short Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis
title_sort reliability and validity of single axial slice vs. multiple slice quantitative measurement of the volume of effusion-synovitis on 3t knee mri in knees with osteoarthritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095125/
https://www.ncbi.nlm.nih.gov/pubmed/37048775
http://dx.doi.org/10.3390/jcm12072691
work_keys_str_mv AT gillesgreg reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT vohraarjun reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT roblesdagoberto reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT taljanovicmihras reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT ashbeckerinl reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT carusochelsea reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT duryeajeffrey reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT bedrickedwardj reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT guermaziali reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis
AT kwohckent reliabilityandvalidityofsingleaxialslicevsmultipleslicequantitativemeasurementofthevolumeofeffusionsynovitison3tkneemriinkneeswithosteoarthritis