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Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery

In this paper, we investigate the effect of sedation using low-dose propofol on patient reported outcome measures (PROMS) in patients undergoing cataract surgery. This is a randomised, single-blinded observational prospective study. Patients undergoing elective cataract surgery using peribulbar anae...

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Autores principales: Ahmed, Mahmoud, Krishna, Yamini, Popova, Petya, Herbert, Rose, Sidaras, Gediminas, Choudhary, Anshoo, Kaye, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095169/
https://www.ncbi.nlm.nih.gov/pubmed/37048825
http://dx.doi.org/10.3390/jcm12072742
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author Ahmed, Mahmoud
Krishna, Yamini
Popova, Petya
Herbert, Rose
Sidaras, Gediminas
Choudhary, Anshoo
Kaye, Stephen B.
author_facet Ahmed, Mahmoud
Krishna, Yamini
Popova, Petya
Herbert, Rose
Sidaras, Gediminas
Choudhary, Anshoo
Kaye, Stephen B.
author_sort Ahmed, Mahmoud
collection PubMed
description In this paper, we investigate the effect of sedation using low-dose propofol on patient reported outcome measures (PROMS) in patients undergoing cataract surgery. This is a randomised, single-blinded observational prospective study. Patients undergoing elective cataract surgery using peribulbar anaesthesia over consecutive cataract lists were selected for this trial. Patients were randomised to receive either no sedation or low-dose propofol (20 to 30 mg followed by 10 mg increments until the patient developed slurred speech alone) prior to the administration of local anaesthesia. Pain, satisfaction, anxiety, needle recall, pulse, and blood pressure (BP) were measured. A total of 97 patients were included, 50 of whom received propofol. There were 4 senior surgeons and anaesthetists. There were no ocular or systemic complications and all patients had uncomplicated surgery. Anxiety (p = 0.026), needle recall (p < 0.001), difference in systolic BP (p = 0.043), and pulse (p = 0.046) were dependent on patient age (p < 0.001) and the use of propofol (p = 0.007). Lower pain was associated with propofol (p = 0.008), as well as lower anxiety (p = 0.002), and increased patient age (p = 0.014). The administration of propofol was significantly associated with lower needle recall (p < 0.001), pre- to post-operative difference in systolic BP (p = 0.029), and mean BP (p = 0.044). Low-dose propofol given immediately prior to administration of local anaesthesia was associated with reduced pain and needle recall, as well as lower BP.
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spelling pubmed-100951692023-04-13 Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery Ahmed, Mahmoud Krishna, Yamini Popova, Petya Herbert, Rose Sidaras, Gediminas Choudhary, Anshoo Kaye, Stephen B. J Clin Med Article In this paper, we investigate the effect of sedation using low-dose propofol on patient reported outcome measures (PROMS) in patients undergoing cataract surgery. This is a randomised, single-blinded observational prospective study. Patients undergoing elective cataract surgery using peribulbar anaesthesia over consecutive cataract lists were selected for this trial. Patients were randomised to receive either no sedation or low-dose propofol (20 to 30 mg followed by 10 mg increments until the patient developed slurred speech alone) prior to the administration of local anaesthesia. Pain, satisfaction, anxiety, needle recall, pulse, and blood pressure (BP) were measured. A total of 97 patients were included, 50 of whom received propofol. There were 4 senior surgeons and anaesthetists. There were no ocular or systemic complications and all patients had uncomplicated surgery. Anxiety (p = 0.026), needle recall (p < 0.001), difference in systolic BP (p = 0.043), and pulse (p = 0.046) were dependent on patient age (p < 0.001) and the use of propofol (p = 0.007). Lower pain was associated with propofol (p = 0.008), as well as lower anxiety (p = 0.002), and increased patient age (p = 0.014). The administration of propofol was significantly associated with lower needle recall (p < 0.001), pre- to post-operative difference in systolic BP (p = 0.029), and mean BP (p = 0.044). Low-dose propofol given immediately prior to administration of local anaesthesia was associated with reduced pain and needle recall, as well as lower BP. MDPI 2023-04-06 /pmc/articles/PMC10095169/ /pubmed/37048825 http://dx.doi.org/10.3390/jcm12072742 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ahmed, Mahmoud
Krishna, Yamini
Popova, Petya
Herbert, Rose
Sidaras, Gediminas
Choudhary, Anshoo
Kaye, Stephen B.
Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery
title Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery
title_full Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery
title_fullStr Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery
title_full_unstemmed Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery
title_short Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery
title_sort low-dose propofol with peribulbar anaesthesia for cataract surgery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095169/
https://www.ncbi.nlm.nih.gov/pubmed/37048825
http://dx.doi.org/10.3390/jcm12072742
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