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Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery
In this paper, we investigate the effect of sedation using low-dose propofol on patient reported outcome measures (PROMS) in patients undergoing cataract surgery. This is a randomised, single-blinded observational prospective study. Patients undergoing elective cataract surgery using peribulbar anae...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095169/ https://www.ncbi.nlm.nih.gov/pubmed/37048825 http://dx.doi.org/10.3390/jcm12072742 |
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author | Ahmed, Mahmoud Krishna, Yamini Popova, Petya Herbert, Rose Sidaras, Gediminas Choudhary, Anshoo Kaye, Stephen B. |
author_facet | Ahmed, Mahmoud Krishna, Yamini Popova, Petya Herbert, Rose Sidaras, Gediminas Choudhary, Anshoo Kaye, Stephen B. |
author_sort | Ahmed, Mahmoud |
collection | PubMed |
description | In this paper, we investigate the effect of sedation using low-dose propofol on patient reported outcome measures (PROMS) in patients undergoing cataract surgery. This is a randomised, single-blinded observational prospective study. Patients undergoing elective cataract surgery using peribulbar anaesthesia over consecutive cataract lists were selected for this trial. Patients were randomised to receive either no sedation or low-dose propofol (20 to 30 mg followed by 10 mg increments until the patient developed slurred speech alone) prior to the administration of local anaesthesia. Pain, satisfaction, anxiety, needle recall, pulse, and blood pressure (BP) were measured. A total of 97 patients were included, 50 of whom received propofol. There were 4 senior surgeons and anaesthetists. There were no ocular or systemic complications and all patients had uncomplicated surgery. Anxiety (p = 0.026), needle recall (p < 0.001), difference in systolic BP (p = 0.043), and pulse (p = 0.046) were dependent on patient age (p < 0.001) and the use of propofol (p = 0.007). Lower pain was associated with propofol (p = 0.008), as well as lower anxiety (p = 0.002), and increased patient age (p = 0.014). The administration of propofol was significantly associated with lower needle recall (p < 0.001), pre- to post-operative difference in systolic BP (p = 0.029), and mean BP (p = 0.044). Low-dose propofol given immediately prior to administration of local anaesthesia was associated with reduced pain and needle recall, as well as lower BP. |
format | Online Article Text |
id | pubmed-10095169 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100951692023-04-13 Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery Ahmed, Mahmoud Krishna, Yamini Popova, Petya Herbert, Rose Sidaras, Gediminas Choudhary, Anshoo Kaye, Stephen B. J Clin Med Article In this paper, we investigate the effect of sedation using low-dose propofol on patient reported outcome measures (PROMS) in patients undergoing cataract surgery. This is a randomised, single-blinded observational prospective study. Patients undergoing elective cataract surgery using peribulbar anaesthesia over consecutive cataract lists were selected for this trial. Patients were randomised to receive either no sedation or low-dose propofol (20 to 30 mg followed by 10 mg increments until the patient developed slurred speech alone) prior to the administration of local anaesthesia. Pain, satisfaction, anxiety, needle recall, pulse, and blood pressure (BP) were measured. A total of 97 patients were included, 50 of whom received propofol. There were 4 senior surgeons and anaesthetists. There were no ocular or systemic complications and all patients had uncomplicated surgery. Anxiety (p = 0.026), needle recall (p < 0.001), difference in systolic BP (p = 0.043), and pulse (p = 0.046) were dependent on patient age (p < 0.001) and the use of propofol (p = 0.007). Lower pain was associated with propofol (p = 0.008), as well as lower anxiety (p = 0.002), and increased patient age (p = 0.014). The administration of propofol was significantly associated with lower needle recall (p < 0.001), pre- to post-operative difference in systolic BP (p = 0.029), and mean BP (p = 0.044). Low-dose propofol given immediately prior to administration of local anaesthesia was associated with reduced pain and needle recall, as well as lower BP. MDPI 2023-04-06 /pmc/articles/PMC10095169/ /pubmed/37048825 http://dx.doi.org/10.3390/jcm12072742 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ahmed, Mahmoud Krishna, Yamini Popova, Petya Herbert, Rose Sidaras, Gediminas Choudhary, Anshoo Kaye, Stephen B. Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery |
title | Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery |
title_full | Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery |
title_fullStr | Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery |
title_full_unstemmed | Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery |
title_short | Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery |
title_sort | low-dose propofol with peribulbar anaesthesia for cataract surgery |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095169/ https://www.ncbi.nlm.nih.gov/pubmed/37048825 http://dx.doi.org/10.3390/jcm12072742 |
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