The Oligomerization Domains of the APC Protein Mediate Liquid-Liquid Phase Separation That Is Phosphorylation Controlled

One of the most important properties of intrinsically disordered proteins is their ability to undergo liquid-liquid phase separation and form droplets. The Adenomatous Polyposis Coli (APC) protein is an IDP that plays a key role in Wnt signaling and mutations in Apc initiate cancer. APC forms drople...

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Detalles Bibliográficos
Autores principales: Bressler, Shachar G., Mitrany, Amit, Wenger, Alon, Näthke, Inke, Friedler, Assaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095272/
https://www.ncbi.nlm.nih.gov/pubmed/37047451
http://dx.doi.org/10.3390/ijms24076478

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