Cargando…

Role of Epithelial-to-Mesenchymal Transition of Retinal Pigment Epithelial Cells in Glaucoma Cupping

Optic nerve head (ONH) cupping is a clinical feature of glaucoma associated with extracellular matrix (ECM) remodelling and lamina cribrosa (LC) fibrosis. Peripapillary atrophy (PPA) occurs commonly in glaucoma, and is characterised by the loss of retinal pigment epithelium (RPE) adjacent to the ONH...

Descripción completa

Detalles Bibliográficos
Autores principales:	O’Driscoll, Eabha, Hughes, Emily, Irnaten, Mustapha, Kuehn, Markus, Wallace, Deborah, O’Brien, Colm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095336/ https://www.ncbi.nlm.nih.gov/pubmed/37048820 http://dx.doi.org/10.3390/jcm12072737

Ejemplares similares

Calcium-Signalling in Human Glaucoma Lamina Cribrosa Myofibroblasts
por: Irnaten, Mustapha, et al.
Publicado: (2023)

Metformin and Glaucoma—Review of Anti-Fibrotic Processes and Bioenergetics
por: Hurley, Daire J., et al.
Publicado: (2021)

The Intertwined Roles of Oxidative Stress and Endoplasmic Reticulum Stress in Glaucoma
por: Hurley, Daire John, et al.
Publicado: (2022)

Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma
por: Irnaten, Mustapha, et al.
Publicado: (2020)

Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma
por: Murphy, Rory, et al.
Publicado: (2022)

p53 and Myofibroblast Apoptosis in Organ Fibrosis
por: McElhinney, Kealan, et al.
Publicado: (2023)

Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells
por: McDonnell, Fiona, et al.
Publicado: (2016)

Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells
por: Kamel, Khalid, et al.
Publicado: (2020)

Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy
por: Zou, Hui, et al.
Publicado: (2020)

Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
por: Tian, Haibin, et al.
Publicado: (2022)

The Role of Epigenetics in the Fibrotic Processes Associated with Glaucoma
por: McDonnell, Fiona, et al.
Publicado: (2014)

Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction
por: Zhou, Mi, et al.
Publicado: (2020)

Inhibitory Effects of Plumbagin on Retinal Pigment Epithelial Cell Epithelial-Mesenchymal Transition In Vitro and In Vivo
por: Chen, Haitin, et al.
Publicado: (2018)

Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells
por: Matoba, Ryo, et al.
Publicado: (2017)

Exosomes mediate an epithelial‐mesenchymal transition cascade in retinal pigment epithelial cells: Implications for proliferative vitreoretinopathy
por: Zhang, Yao, et al.
Publicado: (2020)

Serpentine retinal pigment epithelial tear
por: Maitray, Aditya, et al.
Publicado: (2021)

Human retinal pigment epithelial cells
por: Wang, Lei, et al.
Publicado: (2021)

Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3
por: He, Hua, et al.
Publicado: (2017)

Expression of R345W-Fibulin-3 Induces Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells
por: Zhou, Mi, et al.
Publicado: (2020)

KRT8 phosphorylation regulates the epithelial‐mesenchymal transition in retinal pigment epithelial cells through autophagy modulation
por: Miao, Qi, et al.
Publicado: (2020)

Role of LINC01592 in TGF-β1-induced epithelial-mesenchymal transition of retinal pigment epithelial cells
por: Su, Ying, et al.
Publicado: (2021)

Inhibition of epithelial–mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist
por: Kobayashi, Yuka, et al.
Publicado: (2021)

The retinal pigment epithelium undergoes massive apoptosis during early differentiation and pigmentation of the optic cup
por: Pequignot, M.O., et al.
Publicado: (2011)

Foveolar simple retinal pigment epithelial hamartoma
por: Pujari, Amar, et al.
Publicado: (2018)

The effect of docetaxel on retinal pigment epithelial cells
por: Li, Jialin, et al.
Publicado: (2022)

Acute Retinal Pigment Epitheliitis following Vaccination
por: Sasajima, Hirofumi, et al.
Publicado: (2022)

Snail Involves in the Transforming Growth Factor β1-Mediated Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells
por: Li, Hui, et al.
Publicado: (2011)

Yes‐associated protein is essential for proliferative vitreoretinopathy development via the epithelial‐mesenchymal transition in retinal pigment epithelial fibrosis
por: Zhang, Wei, et al.
Publicado: (2021)

Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells
por: Llorián-Salvador, María, et al.
Publicado: (2022)

Transcriptional regulatory network analysis during epithelial-mesenchymal transformation of retinal pigment epithelium
por: Pratt, Craig H., et al.
Publicado: (2008)

A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells
por: Choudhary, Parul, et al.
Publicado: (2015)

Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy
por: Ishikawa, Keijiro, et al.
Publicado: (2015)

Inhibitory Effect of Bone Morphogenetic Protein 4 in Retinal Pigment Epithelial-Mesenchymal Transition
por: Yao, Haipei, et al.
Publicado: (2016)

Macular Pigment Response to Lutein, Zeaxanthin, and Meso-zeaxanthin Supplementation in Open-Angle Glaucoma: A Randomized Controlled Trial
por: Loughman, James, et al.
Publicado: (2021)

Factor Xa and thrombin induce epithelial-mesenchymal transition by retinal pigment epithelial cells via PDGF-Rβ signaling
por: Bastiaans, Jeroen, et al.
Publicado: (2012)

Nanoscopic Approach to Study the Early Stages of Epithelial to Mesenchymal Transition (EMT) of Human Retinal Pigment Epithelial (RPE) Cells In Vitro
por: Chtcheglova, Lilia A., et al.
Publicado: (2020)

Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors
por: Chen, Yi, et al.
Publicado: (2021)

Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy
por: Yang, Shuai, et al.
Publicado: (2021)

Treatment of retinal pigment epithelial detachment with antiangiogenic therapy
por: Arias, Luis
Publicado: (2010)

Neutrophils Compromise Retinal Pigment Epithelial Barrier Integrity
por: Zhou, Jiehao, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_299ullh93blu7nu1ks8t492hjj