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Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study
Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, especially in patients ventilated for more than 16 h/da...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095348/ https://www.ncbi.nlm.nih.gov/pubmed/37048537 http://dx.doi.org/10.3390/jcm12072453 |
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author | Volpi, Valeria Volpato, Eleonora Compalati, Elena Pierucci, Paola Nicolini, Antonello Lax, Agata Fagetti, Laura Annunziata, Anna Cauteruccio, Rosa Fiorentino, Giuseppe Banfi, Paolo |
author_facet | Volpi, Valeria Volpato, Eleonora Compalati, Elena Pierucci, Paola Nicolini, Antonello Lax, Agata Fagetti, Laura Annunziata, Anna Cauteruccio, Rosa Fiorentino, Giuseppe Banfi, Paolo |
author_sort | Volpi, Valeria |
collection | PubMed |
description | Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, especially in patients ventilated for more than 16 h/day. Intermittent abdominal pressure ventilation (IAPV) differs completely from conventional NVS and consists of a portable ventilator and a corset with Velcro closures as the interface. In our study, the practicability and efficacy of IAPV were studied in three Italian centers monitoring 28 neuromuscular patients using IAPV who were then retrospectively analyzed. The primary outcomes were an improvement in hypoxemia and the normalization of hypercapnia, and the secondary outcome was an improvement in quality of life. Data were collected at baseline (T0) and after two hours of ventilation (T1), with follow-ups at three months (T2) and six months (T3). Statistical significance was found for PaCO(2) over time (F (2.42) = 7.63, p = 0.001) and PaO(2) (W = 0.539, p = 0.033). The time of NVS usage also significantly affected the quality of life (F (2.14) = 6.90, p = 0.010), as seen when comparing T0 and T3. As an alternative ventilation method, IAPV is still relevant today and could become a key part of daytime support, especially for patients who do not tolerate standard daytime NVS with an oral interface. |
format | Online Article Text |
id | pubmed-10095348 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100953482023-04-13 Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study Volpi, Valeria Volpato, Eleonora Compalati, Elena Pierucci, Paola Nicolini, Antonello Lax, Agata Fagetti, Laura Annunziata, Anna Cauteruccio, Rosa Fiorentino, Giuseppe Banfi, Paolo J Clin Med Article Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, especially in patients ventilated for more than 16 h/day. Intermittent abdominal pressure ventilation (IAPV) differs completely from conventional NVS and consists of a portable ventilator and a corset with Velcro closures as the interface. In our study, the practicability and efficacy of IAPV were studied in three Italian centers monitoring 28 neuromuscular patients using IAPV who were then retrospectively analyzed. The primary outcomes were an improvement in hypoxemia and the normalization of hypercapnia, and the secondary outcome was an improvement in quality of life. Data were collected at baseline (T0) and after two hours of ventilation (T1), with follow-ups at three months (T2) and six months (T3). Statistical significance was found for PaCO(2) over time (F (2.42) = 7.63, p = 0.001) and PaO(2) (W = 0.539, p = 0.033). The time of NVS usage also significantly affected the quality of life (F (2.14) = 6.90, p = 0.010), as seen when comparing T0 and T3. As an alternative ventilation method, IAPV is still relevant today and could become a key part of daytime support, especially for patients who do not tolerate standard daytime NVS with an oral interface. MDPI 2023-03-23 /pmc/articles/PMC10095348/ /pubmed/37048537 http://dx.doi.org/10.3390/jcm12072453 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Volpi, Valeria Volpato, Eleonora Compalati, Elena Pierucci, Paola Nicolini, Antonello Lax, Agata Fagetti, Laura Annunziata, Anna Cauteruccio, Rosa Fiorentino, Giuseppe Banfi, Paolo Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study |
title | Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study |
title_full | Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study |
title_fullStr | Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study |
title_full_unstemmed | Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study |
title_short | Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study |
title_sort | is intermittent abdominal pressure ventilation still relevant? a multicenter retrospective pilot study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095348/ https://www.ncbi.nlm.nih.gov/pubmed/37048537 http://dx.doi.org/10.3390/jcm12072453 |
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