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Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study

Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, especially in patients ventilated for more than 16 h/da...

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Autores principales: Volpi, Valeria, Volpato, Eleonora, Compalati, Elena, Pierucci, Paola, Nicolini, Antonello, Lax, Agata, Fagetti, Laura, Annunziata, Anna, Cauteruccio, Rosa, Fiorentino, Giuseppe, Banfi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095348/
https://www.ncbi.nlm.nih.gov/pubmed/37048537
http://dx.doi.org/10.3390/jcm12072453
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author Volpi, Valeria
Volpato, Eleonora
Compalati, Elena
Pierucci, Paola
Nicolini, Antonello
Lax, Agata
Fagetti, Laura
Annunziata, Anna
Cauteruccio, Rosa
Fiorentino, Giuseppe
Banfi, Paolo
author_facet Volpi, Valeria
Volpato, Eleonora
Compalati, Elena
Pierucci, Paola
Nicolini, Antonello
Lax, Agata
Fagetti, Laura
Annunziata, Anna
Cauteruccio, Rosa
Fiorentino, Giuseppe
Banfi, Paolo
author_sort Volpi, Valeria
collection PubMed
description Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, especially in patients ventilated for more than 16 h/day. Intermittent abdominal pressure ventilation (IAPV) differs completely from conventional NVS and consists of a portable ventilator and a corset with Velcro closures as the interface. In our study, the practicability and efficacy of IAPV were studied in three Italian centers monitoring 28 neuromuscular patients using IAPV who were then retrospectively analyzed. The primary outcomes were an improvement in hypoxemia and the normalization of hypercapnia, and the secondary outcome was an improvement in quality of life. Data were collected at baseline (T0) and after two hours of ventilation (T1), with follow-ups at three months (T2) and six months (T3). Statistical significance was found for PaCO(2) over time (F (2.42) = 7.63, p = 0.001) and PaO(2) (W = 0.539, p = 0.033). The time of NVS usage also significantly affected the quality of life (F (2.14) = 6.90, p = 0.010), as seen when comparing T0 and T3. As an alternative ventilation method, IAPV is still relevant today and could become a key part of daytime support, especially for patients who do not tolerate standard daytime NVS with an oral interface.
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spelling pubmed-100953482023-04-13 Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study Volpi, Valeria Volpato, Eleonora Compalati, Elena Pierucci, Paola Nicolini, Antonello Lax, Agata Fagetti, Laura Annunziata, Anna Cauteruccio, Rosa Fiorentino, Giuseppe Banfi, Paolo J Clin Med Article Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, especially in patients ventilated for more than 16 h/day. Intermittent abdominal pressure ventilation (IAPV) differs completely from conventional NVS and consists of a portable ventilator and a corset with Velcro closures as the interface. In our study, the practicability and efficacy of IAPV were studied in three Italian centers monitoring 28 neuromuscular patients using IAPV who were then retrospectively analyzed. The primary outcomes were an improvement in hypoxemia and the normalization of hypercapnia, and the secondary outcome was an improvement in quality of life. Data were collected at baseline (T0) and after two hours of ventilation (T1), with follow-ups at three months (T2) and six months (T3). Statistical significance was found for PaCO(2) over time (F (2.42) = 7.63, p = 0.001) and PaO(2) (W = 0.539, p = 0.033). The time of NVS usage also significantly affected the quality of life (F (2.14) = 6.90, p = 0.010), as seen when comparing T0 and T3. As an alternative ventilation method, IAPV is still relevant today and could become a key part of daytime support, especially for patients who do not tolerate standard daytime NVS with an oral interface. MDPI 2023-03-23 /pmc/articles/PMC10095348/ /pubmed/37048537 http://dx.doi.org/10.3390/jcm12072453 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Volpi, Valeria
Volpato, Eleonora
Compalati, Elena
Pierucci, Paola
Nicolini, Antonello
Lax, Agata
Fagetti, Laura
Annunziata, Anna
Cauteruccio, Rosa
Fiorentino, Giuseppe
Banfi, Paolo
Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study
title Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study
title_full Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study
title_fullStr Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study
title_full_unstemmed Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study
title_short Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study
title_sort is intermittent abdominal pressure ventilation still relevant? a multicenter retrospective pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095348/
https://www.ncbi.nlm.nih.gov/pubmed/37048537
http://dx.doi.org/10.3390/jcm12072453
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