Cargando…

Multi-Targeting Anticancer Activity of a New 4-Thiazolidinone Derivative with Anti-HER2 Antibodies in Human AGS Gastric Cancer Cells

Combining chemotherapy with immunotherapy still remains a regimen in anticancer therapy. Novel 4-thiazolidinone-bearing hybrid molecules possess well-documented anticancer activity, and together with anti-HER2 antibodies, may represent a promising strategy in treating patients with gastric cancer wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gornowicz, Agnieszka, Lesyk, Roman, Czarnomysy, Robert, Holota, Serhii, Shepeta, Yulia, Popławska, Bożena, Podolak, Magdalena, Szymanowski, Wojciech, Bielawski, Krzysztof, Bielawska, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095353/ https://www.ncbi.nlm.nih.gov/pubmed/37047765 http://dx.doi.org/10.3390/ijms24076791

Ejemplares similares

4-Thiazolidinone-Bearing Hybrid Molecules in Anticancer Drug Design
por: Roszczenko, Piotr, et al.
Publicado: (2022)

Anti-HER2 monoclonal antibodies intensify the susceptibility of human gastric cancer cells to etoposide by promoting apoptosis, but not autophagy
por: Gornowicz, Agnieszka, et al.
Publicado: (2021)

Mechanism of anticancer action of novel berenil complex of platinum(II) combined with anti-MUC1 in MCF-7 breast cancer cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2018)

Anticancer Effect of a Novel Octahydropyrazino[2,1-a:5,4-a′]diisoquinoline Derivative and Its Synergistic Action with Nigella sativa in Human Gastric Cancer Cells
por: Czajkowska, Anna, et al.
Publicado: (2017)

Synthesis and Anticancer Activity Evaluation of 5-[2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-thiazolidinones
por: Buzun, Kamila, et al.
Publicado: (2021)

Monoclonal anti-MUC1 antibody with novel octahydropyrazino[2,1-a:5,4-a′]diisoquinoline derivative as a potential multi-targeted strategy in MCF-7 breast cancer cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2019)

Development of Novel Pyridine-Thiazole Hybrid Molecules as Potential Anticancer Agents
por: Ivasechko, Iryna, et al.
Publicado: (2022)

Mucin 1 as a Molecular Target of a Novel Diisoquinoline Derivative Combined with Anti-MUC1 Antibody in AGS Gastric Cancer Cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2021)

LC-PDA-MS and GC-MS Analysis of Scorzonera hispanica Seeds and Their Effects on Human Breast Cancer Cell Lines
por: Lendzion, Karolina, et al.
Publicado: (2022)

The Anticancer Action of a Novel 1,2,4-Triazine Sulfonamide Derivative in Colon Cancer Cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2021)

Autophagy Modulators in Cancer Therapy
por: Buzun, Kamila, et al.
Publicado: (2021)

The molecular mechanism of anticancer action of novel octahydropyrazino[2,1-a:5,4-a′]diisoquinoline derivatives in human gastric cancer cells
por: Pawłowska, Natalia, et al.
Publicado: (2018)

Synthesis and Anticancer Activity of 1,3,4-Thiadiazoles with 3-Methoxyphenyl Substituent
por: Janowska, Sara, et al.
Publicado: (2022)

DNA topoisomerases as molecular targets for anticancer drugs
por: Buzun, Kamila, et al.
Publicado: (2020)

Synthesis, Biological Activity, ADME and Molecular Docking Studies of Novel Ursolic Acid Derivatives as Potent Anticancer Agents
por: Michalak, Olga, et al.
Publicado: (2023)

2-{5-[(Z,2Z)-2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-oxo-2-thioxothiazolidin-3-yl}-3-methylbutanoic Acid as a Potential Anti-Breast Cancer Molecule
por: Buzun, Kamila, et al.
Publicado: (2022)

A novel series of pyrazole-platinum(II) complexes as potential anti-cancer agents that induce cell cycle arrest and apoptosis in breast cancer cells
por: Czarnomysy, Robert, et al.
Publicado: (2018)

The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications
por: Szewczyk-Roszczenko, Olga Klaudia, et al.
Publicado: (2023)

A Facile Synthesis and Anticancer Activity Evaluation of Spiro[Thiazolidinone-Isatin] Conjugates
por: Kaminskyy, Danylo, et al.
Publicado: (2011)

Evaluation of Anticancer and Antibacterial Activity of Four 4-Thiazolidinone-Based Derivatives
por: Skóra, Bartosz, et al.
Publicado: (2022)

Cytotoxic efficacy of a novel dinuclear platinum(II) complex used with anti-MUC1 in human breast cancer cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2014)

The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2015)

Synergistic action of cisplatin and echistatin in MDA-MB-231 breast cancer cells
por: Czarnomysy, Robert, et al.
Publicado: (2016)

5-Ene-4-thiazolidinones – An efficient tool in medicinal chemistry
por: Kaminskyy, Danylo, et al.
Publicado: (2017)

Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-b][1,2,4]triazole-6(5H)-ones as Possible Anticancer Agents
por: Holota, Serhii, et al.
Publicado: (2021)

Effect of 2nd and 3rd generation PAMAM dendrimers on proliferation, differentiation, and pro-inflammatory cytokines in human keratinocytes and fibroblasts
por: Czarnomysy, Robert, et al.
Publicado: (2019)

Evaluation of the Anticancer Activities of Novel Transition Metal Complexes with Berenil and Nitroimidazole
por: Czarnomysy, Robert, et al.
Publicado: (2020)

Phytochemical Composition and Biological Activities of Scorzonera Species
por: Lendzion, Karolina, et al.
Publicado: (2021)

New 1,3,4-Thiadiazole Derivatives with Anticancer Activity
por: Janowska, Sara, et al.
Publicado: (2022)

The Effect of Novel 7-methyl-5-phenyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine Sulfonamide Derivatives on Apoptosis and Autophagy in DLD-1 and HT-29 Colon Cancer Cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2020)

Which salivary components can differentiate metabolic obesity?
por: Ostrowska, Lucyna, et al.
Publicado: (2020)

Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones
por: Havrylyuk, Dmytro, et al.
Publicado: (2013)

Selenium Compounds as Novel Potential Anticancer Agents
por: Radomska, Dominika, et al.
Publicado: (2021)

Selenium as a Bioactive Micronutrient in the Human Diet and Its Cancer Chemopreventive Activity
por: Radomska, Dominika, et al.
Publicado: (2021)

An Overview of the Importance of Transition-Metal Nanoparticles in Cancer Research
por: Szewczyk, Olga Klaudia, et al.
Publicado: (2022)

Biosynthesized Gold, Silver, Palladium, Platinum, Copper, and Other Transition Metal Nanoparticles
por: Roszczenko, Piotr, et al.
Publicado: (2022)

The assessment of sIgA, histatin-5, and lactoperoxidase levels in saliva of adolescents with dental caries
por: Gornowicz, Agnieszka, et al.
Publicado: (2014)

Induction of Cyp450 enzymes by 4-thiazolidinone-based derivatives in 3T3-L1 cells in vitro
por: Szychowski, Konrad A., et al.
Publicado: (2020)

4-Thiazolidinone derivative Les-3833 effectively inhibits viability of human melanoma cells through activating apoptotic mechanisms
por: Finiuk, Nataliya, et al.
Publicado: (2017)

Anti-Cancer Potential of Afzelin towards AGS Gastric Cancer Cells
por: Radziejewska, Iwona, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rpv9mm4gbffmen0fds6uno7lk1