Cargando…
Compression Stockings Improve Lower Legs Symptom in Patients with Pulmonary Artery Hypertension Treated by Pulmonary Vasodilators—A Pilot Study
Pulmonary vasodilators have improved pulmonary arterial hypertension (PAH) symptoms and prognosis; however, the drugs cause some side effects, including lower legs pain, which impair quality of life (QOL). The present study examined if compression stockings improved lower extremity symptoms and QOL...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095423/ https://www.ncbi.nlm.nih.gov/pubmed/37048566 http://dx.doi.org/10.3390/jcm12072484 |
_version_ | 1785024079957327872 |
---|---|
author | Nakashima, Naoko Tahara, Nobuhiro Sugiyama, Yoichi Bekki, Munehisa Maeda-Ogata, Shoko Honda, Akihiro Goto, Chidu Tanaka, Setsuko Fukumoto, Yoshihiro |
author_facet | Nakashima, Naoko Tahara, Nobuhiro Sugiyama, Yoichi Bekki, Munehisa Maeda-Ogata, Shoko Honda, Akihiro Goto, Chidu Tanaka, Setsuko Fukumoto, Yoshihiro |
author_sort | Nakashima, Naoko |
collection | PubMed |
description | Pulmonary vasodilators have improved pulmonary arterial hypertension (PAH) symptoms and prognosis; however, the drugs cause some side effects, including lower legs pain, which impair quality of life (QOL). The present study examined if compression stockings improved lower extremity symptoms and QOL caused by pulmonary vasodilators in PAH patients. We retrospectively enrolled consecutively ten patients with PAH treated by pulmonary vasodilators, who were regularly followed in Kurume University Hospital from January 2022 to June 2022. Oral questionnaire surveys, the Numeric Rating Scale for Pain (NRS) and the Pain Disability Assessment Scale (PDAS), were conducted regarding lower extremity symptoms before wearing elastic stockings and one month later, to evaluate how the lower extremity symptoms affected daily life. All ten patients were female, with a mean age of 50.2 ± 11.5 years, out of whom intravenous prostacyclin analogue (PGI(2)) was administered in five patients. In no intravenous PGI(2) group, NRS score was significantly improved from 4.6 ± 2.3 to 2.8 ± 1.2 (p = 0.037), while from 9.4 ± 1.2 to 5.4 ± 1.6 (p = 0.002) in intravenous PGI(2) group. PDAS score was also significantly improved [no intravenous PGI(2) group; 18.0 (15.0–24.0) to 15.0 (10.0–19.0), intravenous PGI(2) group; 25.0 (17.0–37.0) to 17.0 (5.0–27.0)]. Lower extremity symptoms in patients using pulmonary vasodilators were improved by wearing compression stockings. |
format | Online Article Text |
id | pubmed-10095423 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100954232023-04-13 Compression Stockings Improve Lower Legs Symptom in Patients with Pulmonary Artery Hypertension Treated by Pulmonary Vasodilators—A Pilot Study Nakashima, Naoko Tahara, Nobuhiro Sugiyama, Yoichi Bekki, Munehisa Maeda-Ogata, Shoko Honda, Akihiro Goto, Chidu Tanaka, Setsuko Fukumoto, Yoshihiro J Clin Med Brief Report Pulmonary vasodilators have improved pulmonary arterial hypertension (PAH) symptoms and prognosis; however, the drugs cause some side effects, including lower legs pain, which impair quality of life (QOL). The present study examined if compression stockings improved lower extremity symptoms and QOL caused by pulmonary vasodilators in PAH patients. We retrospectively enrolled consecutively ten patients with PAH treated by pulmonary vasodilators, who were regularly followed in Kurume University Hospital from January 2022 to June 2022. Oral questionnaire surveys, the Numeric Rating Scale for Pain (NRS) and the Pain Disability Assessment Scale (PDAS), were conducted regarding lower extremity symptoms before wearing elastic stockings and one month later, to evaluate how the lower extremity symptoms affected daily life. All ten patients were female, with a mean age of 50.2 ± 11.5 years, out of whom intravenous prostacyclin analogue (PGI(2)) was administered in five patients. In no intravenous PGI(2) group, NRS score was significantly improved from 4.6 ± 2.3 to 2.8 ± 1.2 (p = 0.037), while from 9.4 ± 1.2 to 5.4 ± 1.6 (p = 0.002) in intravenous PGI(2) group. PDAS score was also significantly improved [no intravenous PGI(2) group; 18.0 (15.0–24.0) to 15.0 (10.0–19.0), intravenous PGI(2) group; 25.0 (17.0–37.0) to 17.0 (5.0–27.0)]. Lower extremity symptoms in patients using pulmonary vasodilators were improved by wearing compression stockings. MDPI 2023-03-24 /pmc/articles/PMC10095423/ /pubmed/37048566 http://dx.doi.org/10.3390/jcm12072484 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Brief Report Nakashima, Naoko Tahara, Nobuhiro Sugiyama, Yoichi Bekki, Munehisa Maeda-Ogata, Shoko Honda, Akihiro Goto, Chidu Tanaka, Setsuko Fukumoto, Yoshihiro Compression Stockings Improve Lower Legs Symptom in Patients with Pulmonary Artery Hypertension Treated by Pulmonary Vasodilators—A Pilot Study |
title | Compression Stockings Improve Lower Legs Symptom in Patients with Pulmonary Artery Hypertension Treated by Pulmonary Vasodilators—A Pilot Study |
title_full | Compression Stockings Improve Lower Legs Symptom in Patients with Pulmonary Artery Hypertension Treated by Pulmonary Vasodilators—A Pilot Study |
title_fullStr | Compression Stockings Improve Lower Legs Symptom in Patients with Pulmonary Artery Hypertension Treated by Pulmonary Vasodilators—A Pilot Study |
title_full_unstemmed | Compression Stockings Improve Lower Legs Symptom in Patients with Pulmonary Artery Hypertension Treated by Pulmonary Vasodilators—A Pilot Study |
title_short | Compression Stockings Improve Lower Legs Symptom in Patients with Pulmonary Artery Hypertension Treated by Pulmonary Vasodilators—A Pilot Study |
title_sort | compression stockings improve lower legs symptom in patients with pulmonary artery hypertension treated by pulmonary vasodilators—a pilot study |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095423/ https://www.ncbi.nlm.nih.gov/pubmed/37048566 http://dx.doi.org/10.3390/jcm12072484 |
work_keys_str_mv | AT nakashimanaoko compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy AT taharanobuhiro compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy AT sugiyamayoichi compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy AT bekkimunehisa compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy AT maedaogatashoko compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy AT hondaakihiro compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy AT gotochidu compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy AT tanakasetsuko compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy AT fukumotoyoshihiro compressionstockingsimprovelowerlegssymptominpatientswithpulmonaryarteryhypertensiontreatedbypulmonaryvasodilatorsapilotstudy |