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Intelligent De Novo Design of Novel Antimicrobial Peptides against Antibiotic-Resistant Bacteria Strains

Because of the growing number of clinical antibiotic resistance cases in recent years, novel antimicrobial peptides (AMPs) may be ideal for next-generation antibiotics. This study trained a Wasserstein generative adversarial network with gradient penalty (WGAN-GP) based on known AMPs to generate nov...

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Detalles Bibliográficos
Autores principales: Lin, Tzu-Tang, Yang, Li-Yen, Lin, Chung-Yen, Wang, Ching-Tien, Lai, Chia-Wen, Ko, Chi-Fong, Shih, Yang-Hsin, Chen, Shu-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095442/
https://www.ncbi.nlm.nih.gov/pubmed/37047760
http://dx.doi.org/10.3390/ijms24076788