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Intelligent De Novo Design of Novel Antimicrobial Peptides against Antibiotic-Resistant Bacteria Strains
Because of the growing number of clinical antibiotic resistance cases in recent years, novel antimicrobial peptides (AMPs) may be ideal for next-generation antibiotics. This study trained a Wasserstein generative adversarial network with gradient penalty (WGAN-GP) based on known AMPs to generate nov...
Autores principales: | Lin, Tzu-Tang, Yang, Li-Yen, Lin, Chung-Yen, Wang, Ching-Tien, Lai, Chia-Wen, Ko, Chi-Fong, Shih, Yang-Hsin, Chen, Shu-Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095442/ https://www.ncbi.nlm.nih.gov/pubmed/37047760 http://dx.doi.org/10.3390/ijms24076788 |
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