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Magnetic Resonance-Based Assessment of Optic Nerve Sheath Diameter: A Prospective Observational Cohort Study on Inter- and Intra-Rater Agreement

Background: The measurement of optic nerve sheath diameter (ONSD) as a non-invasive method of estimating intracranial pressure has been widely reported in the literature. However, few studies have evaluated the accuracy of magnetic resonance imaging (MRI) in assessing ONSD measurements, although it...

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Autores principales: Aspide, Raffaele, Bertolini, Giacomo, Belotti, Laura Maria Beatrice, Albini Riccioli, Luca, Toni, Francesco, Mazzatenta, Diego, Palandri, Giorgio, Vetrugno, Luigi, Biasucci, Daniele Guerino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095459/
https://www.ncbi.nlm.nih.gov/pubmed/37048796
http://dx.doi.org/10.3390/jcm12072713
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author Aspide, Raffaele
Bertolini, Giacomo
Belotti, Laura Maria Beatrice
Albini Riccioli, Luca
Toni, Francesco
Mazzatenta, Diego
Palandri, Giorgio
Vetrugno, Luigi
Biasucci, Daniele Guerino
author_facet Aspide, Raffaele
Bertolini, Giacomo
Belotti, Laura Maria Beatrice
Albini Riccioli, Luca
Toni, Francesco
Mazzatenta, Diego
Palandri, Giorgio
Vetrugno, Luigi
Biasucci, Daniele Guerino
author_sort Aspide, Raffaele
collection PubMed
description Background: The measurement of optic nerve sheath diameter (ONSD) as a non-invasive method of estimating intracranial pressure has been widely reported in the literature. However, few studies have evaluated the accuracy of magnetic resonance imaging (MRI) in assessing ONSD measurements, although it is considered a very reliable method, it is not easily repeatable, expensive and is not readily available bedside. Herein, an assessment of the intra- and inter-rater reliability of ONSD assessment using MRI was conducted. Methods: A consecutive, prospective cohort of patients with suspected idiopathic normal-pressure hydrocephalus was analyzed. ONSD MRI measurements of the transverse and sagittal diameters at a distance of 3 mm behind the papilla were evaluated twice each by two expert neuroradiologists. The correlations between MRI examiners were calculated using the concordance correlation coefficient (CCC). Results: Fifty patients were included in the study. ONSD MRI average measurements were substantially higher than clinically expected (>5 mm). Considering intra-rater concordance, only one of the two neuroradiologists achieved an excellent score at CCC. Only a moderate inter-observer CCC for MRI assessment was found at all diameters. Conclusions: The use of a widespread MRI sequence (3D T1) to measure ONSD is not an accurate method since it may overestimate measurements and is dependent upon an operator.
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spelling pubmed-100954592023-04-13 Magnetic Resonance-Based Assessment of Optic Nerve Sheath Diameter: A Prospective Observational Cohort Study on Inter- and Intra-Rater Agreement Aspide, Raffaele Bertolini, Giacomo Belotti, Laura Maria Beatrice Albini Riccioli, Luca Toni, Francesco Mazzatenta, Diego Palandri, Giorgio Vetrugno, Luigi Biasucci, Daniele Guerino J Clin Med Article Background: The measurement of optic nerve sheath diameter (ONSD) as a non-invasive method of estimating intracranial pressure has been widely reported in the literature. However, few studies have evaluated the accuracy of magnetic resonance imaging (MRI) in assessing ONSD measurements, although it is considered a very reliable method, it is not easily repeatable, expensive and is not readily available bedside. Herein, an assessment of the intra- and inter-rater reliability of ONSD assessment using MRI was conducted. Methods: A consecutive, prospective cohort of patients with suspected idiopathic normal-pressure hydrocephalus was analyzed. ONSD MRI measurements of the transverse and sagittal diameters at a distance of 3 mm behind the papilla were evaluated twice each by two expert neuroradiologists. The correlations between MRI examiners were calculated using the concordance correlation coefficient (CCC). Results: Fifty patients were included in the study. ONSD MRI average measurements were substantially higher than clinically expected (>5 mm). Considering intra-rater concordance, only one of the two neuroradiologists achieved an excellent score at CCC. Only a moderate inter-observer CCC for MRI assessment was found at all diameters. Conclusions: The use of a widespread MRI sequence (3D T1) to measure ONSD is not an accurate method since it may overestimate measurements and is dependent upon an operator. MDPI 2023-04-05 /pmc/articles/PMC10095459/ /pubmed/37048796 http://dx.doi.org/10.3390/jcm12072713 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Aspide, Raffaele
Bertolini, Giacomo
Belotti, Laura Maria Beatrice
Albini Riccioli, Luca
Toni, Francesco
Mazzatenta, Diego
Palandri, Giorgio
Vetrugno, Luigi
Biasucci, Daniele Guerino
Magnetic Resonance-Based Assessment of Optic Nerve Sheath Diameter: A Prospective Observational Cohort Study on Inter- and Intra-Rater Agreement
title Magnetic Resonance-Based Assessment of Optic Nerve Sheath Diameter: A Prospective Observational Cohort Study on Inter- and Intra-Rater Agreement
title_full Magnetic Resonance-Based Assessment of Optic Nerve Sheath Diameter: A Prospective Observational Cohort Study on Inter- and Intra-Rater Agreement
title_fullStr Magnetic Resonance-Based Assessment of Optic Nerve Sheath Diameter: A Prospective Observational Cohort Study on Inter- and Intra-Rater Agreement
title_full_unstemmed Magnetic Resonance-Based Assessment of Optic Nerve Sheath Diameter: A Prospective Observational Cohort Study on Inter- and Intra-Rater Agreement
title_short Magnetic Resonance-Based Assessment of Optic Nerve Sheath Diameter: A Prospective Observational Cohort Study on Inter- and Intra-Rater Agreement
title_sort magnetic resonance-based assessment of optic nerve sheath diameter: a prospective observational cohort study on inter- and intra-rater agreement
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095459/
https://www.ncbi.nlm.nih.gov/pubmed/37048796
http://dx.doi.org/10.3390/jcm12072713
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