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Stearoyl-CoA Desaturases1 Accelerates Non-Small Cell Lung Cancer Metastasis by Promoting Aromatase Expression to Improve Estrogen Synthesis

Metastases contribute to the low survival rate of non-small cell lung cancer (NSCLC) patients. Targeting lipid metabolism for anticancer therapies is attractive. Accumulative evidence shows that stearoyl-CoA desaturases1 (SCD1), a key enzyme in lipid metabolism, enables tumor metastasis and the unde...

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Detalles Bibliográficos
Autores principales: Chen, Jiaping, Wang, Yangwei, Meng, Wangyang, Zhao, Rong, Lin, Wei, Xiao, Han, Liao, Yongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095487/
https://www.ncbi.nlm.nih.gov/pubmed/37047797
http://dx.doi.org/10.3390/ijms24076826