Cargando…
Doxorubicin–Mediated miR–433 Expression on Exosomes Promotes Bystander Senescence in Multiple Myeloma Cells in a DDR–Independent Manner
The success of senescence-based anticancer therapies relies on their anti-proliferative power and on their ability to trigger anti-tumor immune responses. Indeed, genotoxic drug-induced senescence increases the expression of NK cell-activating ligands on multiple myeloma (MM) cells, boosting NK cell...
Autores principales: | Vulpis, Elisabetta, Cuollo, Lorenzo, Borrelli, Cristiana, Antonangeli, Fabrizio, Masuelli, Laura, Cippitelli, Marco, Fionda, Cinzia, Caracciolo, Giulio, Petrucci, Maria Teresa, Santoni, Angela, Zingoni, Alessandra, Soriani, Alessandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095495/ https://www.ncbi.nlm.nih.gov/pubmed/37047835 http://dx.doi.org/10.3390/ijms24076862 |
Ejemplares similares
-
Cross-Dressing of Multiple Myeloma Cells Mediated by Extracellular Vesicles Conveying MIC and ULBP Ligands Promotes NK Cell Killing
por: Vulpis, Elisabetta, et al.
Publicado: (2023) -
Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance
por: Zingoni, Alessandra, et al.
Publicado: (2017) -
NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma
por: Fionda, Cinzia, et al.
Publicado: (2015) -
Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay
por: Abruzzese, Maria Pia, et al.
Publicado: (2016) -
Key Role of the CD56(low)CD16(low) Natural Killer Cell Subset in the Recognition and Killing of Multiple Myeloma Cells
por: Vulpis, Elisabetta, et al.
Publicado: (2018)