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Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles
The rate of monozygotic twinning (MZT) has seen a gradual increase in recent years. Numerous parameters involved in ART procedures are blamed for this surge, even though the exact explanation is as yet unknown. Our study’s objectives were to determine the risk variables for monozygotic twinning afte...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095500/ https://www.ncbi.nlm.nih.gov/pubmed/37048676 http://dx.doi.org/10.3390/jcm12072593 |
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author | Kadam, Nikit Woodhead, George Kellam, Louise Campbell, Alison Jayaprakasan, Kanna |
author_facet | Kadam, Nikit Woodhead, George Kellam, Louise Campbell, Alison Jayaprakasan, Kanna |
author_sort | Kadam, Nikit |
collection | PubMed |
description | The rate of monozygotic twinning (MZT) has seen a gradual increase in recent years. Numerous parameters involved in ART procedures are blamed for this surge, even though the exact explanation is as yet unknown. Our study’s objectives were to determine the risk variables for monozygotic twinning after ART and to estimate their prevalence. We examined 25,794 IVF cycles for the incidence of monozygotic twinning in this observational analysis. Our study, which was carried out across seven tertiary IVF centres over the course of four years, found an overall MZT rate of 0.37% per embryo transfer procedure and 0.88% of all pregnancies. Monozygotic twinning was more commonly seen in fresh single-embryo transfer (SET) and blastocyst transfer cycles. Larger multicentre studies are needed to explore the potential risk variables. |
format | Online Article Text |
id | pubmed-10095500 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100955002023-04-13 Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles Kadam, Nikit Woodhead, George Kellam, Louise Campbell, Alison Jayaprakasan, Kanna J Clin Med Brief Report The rate of monozygotic twinning (MZT) has seen a gradual increase in recent years. Numerous parameters involved in ART procedures are blamed for this surge, even though the exact explanation is as yet unknown. Our study’s objectives were to determine the risk variables for monozygotic twinning after ART and to estimate their prevalence. We examined 25,794 IVF cycles for the incidence of monozygotic twinning in this observational analysis. Our study, which was carried out across seven tertiary IVF centres over the course of four years, found an overall MZT rate of 0.37% per embryo transfer procedure and 0.88% of all pregnancies. Monozygotic twinning was more commonly seen in fresh single-embryo transfer (SET) and blastocyst transfer cycles. Larger multicentre studies are needed to explore the potential risk variables. MDPI 2023-03-30 /pmc/articles/PMC10095500/ /pubmed/37048676 http://dx.doi.org/10.3390/jcm12072593 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Brief Report Kadam, Nikit Woodhead, George Kellam, Louise Campbell, Alison Jayaprakasan, Kanna Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
title | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
title_full | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
title_fullStr | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
title_full_unstemmed | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
title_short | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
title_sort | odds and predictors of monozygotic twinning in a multicentre cohort of 25,794 ivf cycles |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095500/ https://www.ncbi.nlm.nih.gov/pubmed/37048676 http://dx.doi.org/10.3390/jcm12072593 |
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