Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse

Transcriptomics and phosphoproteomics were carried out in the cerebral cortex of B6.Cg-Mapttm1(EGFP)Klt (tau knockout: tau-KO) and wild-type (WT) 12 month-old mice to learn about the effects of tau ablation. Compared with WT mice, tau-KO mice displayed reduced anxiety-like behavior and lower fear ex...

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Detalles Bibliográficos
Autores principales: Andrés-Benito, Pol, Flores, África, Busquet-Areny, Sara, Carmona, Margarita, Ausín, Karina, Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, Del Rio, José Antonio, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Ferrer, Isidro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095510/
https://www.ncbi.nlm.nih.gov/pubmed/37047532
http://dx.doi.org/10.3390/ijms24076559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095510/
https://www.ncbi.nlm.nih.gov/pubmed/37047532
http://dx.doi.org/10.3390/ijms24076559

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