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Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse
Transcriptomics and phosphoproteomics were carried out in the cerebral cortex of B6.Cg-Mapttm1(EGFP)Klt (tau knockout: tau-KO) and wild-type (WT) 12 month-old mice to learn about the effects of tau ablation. Compared with WT mice, tau-KO mice displayed reduced anxiety-like behavior and lower fear ex...
Autores principales: | Andrés-Benito, Pol, Flores, África, Busquet-Areny, Sara, Carmona, Margarita, Ausín, Karina, Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, Del Rio, José Antonio, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Ferrer, Isidro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095510/ https://www.ncbi.nlm.nih.gov/pubmed/37047532 http://dx.doi.org/10.3390/ijms24076559 |
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